Biotecnología microbiana y salud

2022

A Novel L-Asparaginase from Enterobacter sp. Strain M55 from Maras Salterns in Peru

Hurtado, A., Flores-Santos, J. C., Flores-Fernández, C. N., Saavedra, S., Santos, J. H. P. M., Pessoa-Júnior, A., Lienqueo, M. E., Bayro, M. J. & Zavaleta, A. I., 2022, In: Chemical and Biochemical Engineering Quarterly. 36, 2, p. 167-173 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Association between Ancestry-Specific 6q25 Variants and Breast Cancer Subtypes in Peruvian Women

Zavala, V. A., Casavilca-Zambrano, S., Navarro-Vásquez, J., Castañeda, C. A., Valencia, G., Morante, Z., Calderón, M., Abugattas, J. E., Gómez, H., Fuentes, H. A., Liendo-Picoaga, R., Cotrina, J. M., Monge, C., Neciosup, S. P., Huntsman, S., Hu, D., Sánchez, S. E., Williams, M. A., Núñez-Marrero, A. & Godoy, L. & 11 others, Hechmer, A., Olshen, A. B., Dutil, J., Ziv, E., Zabaleta, J., Gelaye, B., Vásquez, J., Gálvez-Nino, M., Enriquez-Vera, D., Vidaurre, T. & Fejerman, L., Aug 2022, In: Cancer Epidemiology Biomarkers and Prevention. 31, 8 August, p. 1602-1609 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Association between PIK3CA Mutations in Blood and Tumor-Infiltrating Lymphocytes in Peruvian Breast Cancer Patients

Castaneda, C. A., Castillo, M., Bernabe, L. A., Suarez, N., Romero, A., Sanchez, J., Torres, E., Enciso, J., Tello, K., Enciso, N., Velarde, M., De La Cruz, M., Dunstan, J., Cotrina, J. M., Abugattas, J., Pinillos, M. A., Roque, K., Fuentes, H., Poquioma, E. & Guerra, H. & 1 others, Gomez, H. L., 2022, In: Asian Pacific Journal of Cancer Prevention. 23, 10, p. 3331-3337 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Nanoencapsulation of antioxidant peptides from Lupinus mutabilis in chitosan nanoparticles obtained by ionic gelling and spray freeze drying intended for colonic delivery

Intiquilla, A., Jiménez-Aliaga, K., Iris Zavaleta, A., Gamboa, A., Caro, N., Diaz, M., Gotteland, M., Abugoch, L. & Tapia, C., Dec 2022, In: Food Bioscience. 50, 102055.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Protection against Oxidative Stress and Metabolic Alterations by Synthetic Peptides Derived from Erythrina edulis Seed Protein

Rodríguez-Arana, N., Jiménez-Aliaga, K., Intiquilla, A., León, J. A., Flores, E., Zavaleta, A. I., Izaguirre, V., Solis-Calero, C. & Hernández-Ledesma, B., Nov 2022, In: Antioxidants. 11, 11, 2101.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

2021

Albumin from erythrina edulis (Pajuro) as a promising source of multifunctional peptides

Palma-Albino, C., Intiquilla, A., Jiménez-Aliaga, K., Rodríguez-Arana, N., Solano, E., Flores, E., Zavaleta, A. I., Izaguirre, V. & Hernández-Ledesma, B., Nov 2021, In: Antioxidants. 10, 11, 1722.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Antimicrobial peptides purified from hydrolysates of kanihua (Chenopodium pallidicaule Aellen) seed protein fractions

Moscoso-Mujica, G., Zavaleta, A. I., Mujica, Á., Arnao, I., Moscoso-Neira, C., Santos, M. & Sánchez, J., 30 Oct 2021, In: Food Chemistry. 360, 129951.

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Stereotactic or conformal radiotherapy for adrenal metastases: Patient characteristics and outcomes in a multicenter analysis

Buergy, D., Würschmidt, F., Gkika, E., Hörner-Rieber, J., Knippen, S., Gerum, S., Balermpas, P., Henkenberens, C., Voglhuber, T., Kornhuber, C., Barczyk, S., Röper, B., Rashid, A., Blanck, O., Wittig, A., Herold, H. U., Brunner, T. B., Klement, R. J., Kahl, K. H. & Ciernik, I. F. & 8 others, Ottinger, A., Izaguirre, V., Putz, F., König, L., Hoffmann, M., Combs, S. E., Guckenberger, M. & Boda-Heggemann, J., 15 Jul 2021, In: International Journal of Cancer. 149, 2, p. 358-370 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

27 Scopus citations

2020

Human epidermal growth factor receptor 2–positive breast cancer is associated with Indigenous American ancestry in Latin American women

COLUMBUS Consortium, May 2020, In: Cancer Research. 80, 9, p. 1893-1901 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

the International Immuno-Oncology Biomarker Working Group, 1 Dec 2020, In: npj Breast Cancer. 6, 1, 17.

Research output: Contribution to journal › Article › peer-review

Open Access

120 Scopus citations

Production and Characterization of Extremophilic Proteinases From a New Enzyme Source, Barrientosiimonas sp. V9

Flores-Santos, J. C., Zavaleta, A. I., Flores-Fernández, C. N., Chávez-Hidalgo, E., Izaguirre, V. & Brandelli, A., 1 Mar 2020, In: Applied Biochemistry and Biotechnology. 190, 3, p. 1060-1073 14 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Purification of Pseudomonas sp. proteases through aqueous biphasic systems as an alternative source to obtain bioactive protein hydrolysates

Pillaca-Pullo, O. S., Intiquilla, A., Santos, J. H. P. M., Sánchez-Moguel, I., Brandelli, A. & Zavaleta, A. I., 1 Jan 2020, In: Biotechnology Progress.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Standard anthracycline based versus docetaxel-capecitabine in early high clinical and/or genomic risk breast cancer in the EORTC 10041/BIG 3-04 MINDACT phase III trial

MINDACT investigators and the TRANSBIG Consortium, 10 Apr 2020, In: Journal of Clinical Oncology. 38, 11, p. 1186-1197 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

2019

Latin American Study of Hereditary Breast and Ovarian Cancer LACAM: A Genomic Epidemiology Approach

LACAM Study, 20 Dec 2019, In: Frontiers in Oncology. 9, 1429.

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Level of tumor-infiltrating lymphocytes and density of infiltrating immune cells in different malignancies

Castaneda, C. A., Castillo, M., Aliaga, K., Bernabe, L. A., Casavilca, S., Sanchez, J., Torres-Cabala, C. A., Gomez, H. L., Mas, L., Dunstan, J., Cotrina, J. M., Abugattas, J., Chavez, I., Ruiz, E., Montenegro, P., Rojas, V., Orrego, E., Galvez-Nino, M., Felix, B. & Landa-Baella, M. P. & 5 others, Vidaurre, T., Villa, M. R., Zevallos, R., Taxa, L. & Guerra, H., 2019, In: Biomarkers in Medicine. 13, 17, p. 1481-1491 11 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Molecular characterization of protease producing Idiomarina species isolated from Peruvian saline environments

Flores-Fernández, C. N., Chávez-Hidalgo, E., Santos, M., Zavaleta, A. I. & Arahal, D. R., 28 Sep 2019, In: Microbiology and Biotechnology Letters. p. 401-411 11 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Neoadjuvant letrozole plus taselisib versus letrozole plus placebo in postmenopausal women with oestrogen receptor-positive, HER2-negative, early-stage breast cancer (LORELEI): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial

Saura, C., Hlauschek, D., Oliveira, M., Zardavas, D., Jallitsch-Halper, A., de la Peña, L., Nuciforo, P., Ballestrero, A., Dubsky, P., Lombard, J. M., Vuylsteke, P., Castaneda, C. A., Colleoni, M., Santos Borges, G., Ciruelos, E., Fornier, M., Boer, K., Bardia, A., Wilson, T. R. & Stout, T. J. & 6 others, Hsu, J. Y., Shi, Y., Piccart, M., Gnant, M., Baselga, J. & de Azambuja, E., Sep 2019, In: The Lancet Oncology. 20, 9, p. 1226-1238 13 p.

Research output: Contribution to journal › Article › peer-review

83 Scopus citations

Novel antioxidant peptides obtained by alcalase hydrolysis of Erythrina edulis (pajuro) protein

Intiquilla, A., Jiménez-Aliaga, K., Guzmán, F., Alvarez, C. A., Zavaleta, A. I., Izaguirre, V. & Hernández-Ledesma, B., 30 Mar 2019, In: Journal of the Science of Food and Agriculture. 99, 5, p. 2420-2427 8 p.

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Novel extremophilic proteases from Pseudomonas aeruginosa M211 and their application in the hydrolysis of dried distiller's grain with solubles

Flores-Fernández, C. N., Cárdenas-Fernández, M., Dobrijevic, D., Jurlewicz, K., Zavaleta, A. I., Ward, J. M. & Lye, G. J., 1 Jan 2019, In: Biotechnology Progress.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Novel extremophilic proteases from Pseudomonas aeruginosa M211 and their application in the hydrolysis of dried distiller's grain with solubles

Flores-Fernández, C. N., Cárdenas-Fernández, M., Dobrijevic, D., Jurlewicz, K., Zavaleta, A. I., Ward, J. M. & Lye, G. J., 1 Jan 2019, In: Biotechnology Progress. 35, 1, e2728.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Predominance of lactobacillus plantarum strains in peruvian amazonian fruits

Sánchez, J., Vegas, C., Zavaleta, A. I. & Esteve-Zarzoso, B., 1 Jan 2019, In: Polish Journal of Microbiology. p. 127-139 13 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Prognostic implications of residual disease tumor-infiltrating lymphocytes and residual cancer burden in triple-negative breast cancer patients after neoadjuvant chemotherapy

Luen, S. J., Salgado, R., Dieci, M. V., Vingiani, A., Curigliano, G., Gould, R. E., Castaneda, C., D'Alfonso, T., Sanchez, J., Cheng, E., Andreopoulou, E., Castillo, M., Adams, S., Demaria, S., Symmans, W. F., Michiels, S. & Loi, S., 1 Feb 2019, In: Annals of Oncology. 30, 2, p. 236-242 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

144 Scopus citations

2018

Breast cancer subtype and survival among Indigenous American women in Peru

Tamayo, L. I., Vidaurre, T., Vásquez, J. N., Casavilca, S., Aramburu Palomino, J. I., Calderon, M., Abugattas, J. E., Gomez, H. L., Castaneda, C. A., Song, S., Cherry, D., Rauscher, G. H. & Fejerman, L., Sep 2018, In: PLoS ONE. 13, 9, e0201287.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

Distribution of tumor-infiltrating immune cells in glioblastoma

Orrego, E., Castaneda, C. A., Castillo, M., Bernabe, L. A., Casavilca, S., Chakravarti, A., Meng, W., Garcia-Corrochano, P., Villa-Robles, M. R., Zevallos, R., Mejia, O., Deza, P., Belmar-Lopez, C. & Ojeda, L., 2018, In: CNS oncology. 7, 4, 0037.

Research output: Contribution to journal › Article › peer-review

Open Access

44 Scopus citations

Optimization of fermentation process conditions for chili pepper (Capsicum frutescens) fruit using response surface methodology

Translated title of the contribution: Optimization of fermentation process conditions for chili pepper (Capsicum frutescens) fruit using response surface methodologyVegas, C., Zavaleta, A. I. & Zarzoso, B., 2018, In: Agronomia Colombiana. 36, 1, p. 88-96 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Optimization of fermentation process conditions for chili pepper (Capsicum frutescens) fruit using response surface methodology

Vegas, C., Zavaleta, A. I. & Zarzoso, B., 1 Jan 2018, In: Agronomia Colombiana. p. 88-96 9 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Production of antioxidant hydrolyzates from a lupinus mutabilis (Tarwi) protein concentrate with alcalase: Optimization by response surface methodology

Intiquilla, A., Jiménez-Aliaga, K., Zavaleta, A. I. & Hernández-Ledesma, B., Jun 2018, In: Natural Product Communications. 13, 6, p. 751-756 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

Sequence determination and homology modeling of lipase from Marinobacter sp. LB

Avila, J., Zavaleta, A. I., Palomino, M. & Solis-Calero, C., 1 Aug 2018, In: Revista Peruana de Biologia. p. 249-258 10 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

2017

Fractionation and electrophoretic characterization of (Chenopodium pallidicaule Aellen) kanihua seed proteins

Moscoso-Mujica, G., Zavaleta, A., Mujica, Á., Santos, M. & Calixto, R., 1 Jan 2017, In: Revista Chilena de Nutricion. p. 144-152 9 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Glioblastoma of pineal region: report of four cases and literature review

Orrego, E., Casavilca, S., Garcia-Corrochano, P., Rojas-Meza, S., Castillo, M. & Castaneda, C. A., 1 Oct 2017, In: CNS oncology. 6, 4, p. 251-259 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

2016

Interobserver Agreement Between Pathologists Assessing Tumor-Infiltrating Lymphocytes (TILs) in Breast Cancer Using Methodology Proposed by the International TILs Working Group

Swisher, S. K., Wu, Y., Castaneda, C. A., Lyons, G. R., Yang, F., Tapia, C., Wang, X., Casavilca, S. A. A., Bassett, R., Castillo, M., Sahin, A. & Mittendorf, E. A., 1 Jul 2016, In: Annals of Surgical Oncology. 23, 7, p. 2242-2248 7 p.

Research output: Contribution to journal › Article › peer-review

90 Scopus citations

2015

Características clínicas y toxicidad del tratamiento de tuberculosis en pacientes con cáncer

Translated title of the contribution: Clinical features and toxicity of tuberculosis treatment in patients with cancerCuéllar, L., Castañeda, C. A., Rojas, K., Flores, C., Dolores-Cerna, K., Castillo, M. & Vicente, W., 2015, In: Revista Peruana de Medicina Experimental y Salud Publica. 32, 2, p. 272-277 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Combined label-free quantitative proteomics and microRNA expression analysis of breast cancer unravel molecular differences with clinical implications

Gámez-Pozo, A., Berges-Soria, J., Arevalillo, J. M., Nanni, P., López-Vacas, R., Navarro, H., Grossmann, J., Castaneda, C. A., Main, P., Díaz-Almirón, M., Espinosa, E., Ciruelos, E. & Fresno Vara, J. Á., 1 Jun 2015, In: Cancer Research. 75, 11, p. 2243-2253 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

45 Scopus citations

Prognostic factors for patients with newly diagnosed brain metastasis from breast cancer

Castaneda, C. A., Flores, R., Rojas, K. Y., Castillo, M., Dolores-Cerna, K., Flores, C., Belmar-Lopez, C., Milla, E. & Gomez, H., 2015, In: CNS oncology. 4, 3, p. 137-145 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

8 Scopus citations

2014

PIK3CA mutations in Peruvian patients with HER2-amplified and triple negative non-metastatic breast cancers

Castaneda, C. A., Lopez-Ilasaca, M., Pinto, J. A., Chirinos-Arias, M., Doimi, F., Neciosup, S. P., Rojas, K. I., Vidaurre, T., Balko, J. M., Arteaga, C. L. & Gomez, H. L., 1 Dec 2014, In: Hematology/ Oncology and Stem Cell Therapy. 7, 4, p. 142-148 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

2011

Synthesis and evaluation of arylquinones as BACE1 inhibitors, β-amyloid peptide aggregation inhibitors, and destabilizers of preformed β-amyloid fibrils

Ortega, A., Rincón, Á., Jiménez-Aliaga, K. L., Bermejo-Bescós, P., Martín-Aragón, S., Molina, M. T. & Csákÿ, A. G., 15 Apr 2011, In: Bioorganic and Medicinal Chemistry Letters. 21, 8, p. 2183-2187 5 p.

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

2010

In vitro antiamyloidogenic properties of 1,4-naphthoquinones

Bermejo-Bescós, P., Martín-Aragón, S., Jiménez-Aliaga, K. L., Ortega, A., Molina, M. T., Buxaderas, E., Orellana, G. & Csákÿ, A. G., Sep 2010, In: Biochemical and Biophysical Research Communications. 400, 1, p. 169-174 6 p.

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

2009

Serotyping of Avibacterium paragallinarum isolates from Peru

Mendoza-Espinoza, A., Terzolo, H. R., Delgado, R. I., Zavaleta, A. I., Koga, Y. & Huberman, Y. D., 1 Sep 2009, In: Avian Diseases. p. 462-465 4 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

2008

Amplified 16S ribosomal DNA restriction analysis for identification of Avibacterium paragallinarum

Mendoza-Espinoza, A., Koga, Y. & Zavaleta, A. I., 1 Mar 2008, In: Avian Diseases. p. 54-58 5 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Expression and substrate specificity of a recombinant cysteine proteinase B of Leishmania braziliensis

Lanfranco, M. F., Loayza-Muro, R., Clark, D., Núñez, R., Zavaleta, A. I., Jimenez, M., Meldal, M., Coombs, G. H., Mottram, J. C., Izidoro, M., Juliano, M. A., Juliano, L. & Arévalo, J., Oct 2008, In: Molecular and Biochemical Parasitology. 161, 2, p. 91-100 10 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

2006

Distribution of paraoxonase-1 gene polymorphisms and enzyme activity in a Peruvian population

Cataño, H. C., Cueva, J. L., Cardenas, A. M., Izaguirre, V., Zavaleta, A. I., Carranza, E. & Hernández, A. F., 1 Dec 2006, In: Environmental and Molecular Mutagenesis. p. 699-706 8 p.

Research output: Contribution to journal › Article › peer-review