Adrenal response to tolbutamide-induced hypoglycemia in high altitude dwellers

Enrique Urdanivia, Fausto Garmendia, José Torres, Mario Zubiate, Raúl Tamayo

Research output: Contribution to journalArticle

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Abstract

Adrenal response to tolbutamideinduced hypoglycemia was studied in 23 normal men born and living at high altitude (Morococha, Peru, 4,540 m) and compared to 23 men born and living near sea level. Fasting blood sugar was significantly lower in the high altitude dwellers (HAD) and this difference persisted throughout the test period. The blood glucose decrement at 30 min was significantly less in the HAD. Plasma cortisol response was significantly higher at 30 and 60 min in the HAD. Peak cortisol level occurred earlier in the HAD than in men living at sea level. The absolute cortisol increment at 30 min was significantly greater in the HAD. © 1975 by The Endocrine Society.
Original languageAmerican English
Pages (from-to)717-719
Number of pages3
JournalJournal of Clinical Endocrinology and Metabolism
DOIs
StatePublished - 1 Jan 1975

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