TY - JOUR
T1 - Adrenal response to tolbutamide-induced hypoglycemia in high altitude dwellers
AU - Urdanivia, Enrique
AU - Garmendia, Fausto
AU - Torres, José
AU - Zubiate, Mario
AU - Tamayo, Raúl
PY - 1975/1/1
Y1 - 1975/1/1
N2 - Adrenal response to tolbutamideinduced hypoglycemia was studied in 23 normal men born and living at high altitude (Morococha, Peru, 4,540 m) and compared to 23 men born and living near sea level. Fasting blood sugar was significantly lower in the high altitude dwellers (HAD) and this difference persisted throughout the test period. The blood glucose decrement at 30 min was significantly less in the HAD. Plasma cortisol response was significantly higher at 30 and 60 min in the HAD. Peak cortisol level occurred earlier in the HAD than in men living at sea level. The absolute cortisol increment at 30 min was significantly greater in the HAD. © 1975 by The Endocrine Society.
AB - Adrenal response to tolbutamideinduced hypoglycemia was studied in 23 normal men born and living at high altitude (Morococha, Peru, 4,540 m) and compared to 23 men born and living near sea level. Fasting blood sugar was significantly lower in the high altitude dwellers (HAD) and this difference persisted throughout the test period. The blood glucose decrement at 30 min was significantly less in the HAD. Plasma cortisol response was significantly higher at 30 and 60 min in the HAD. Peak cortisol level occurred earlier in the HAD than in men living at sea level. The absolute cortisol increment at 30 min was significantly greater in the HAD. © 1975 by The Endocrine Society.
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U2 - 10.1210/jcem-40-4-717
DO - 10.1210/jcem-40-4-717
M3 - Article
SN - 0021-972X
SP - 717
EP - 719
JO - Journal of Clinical Endocrinology and Metabolism
JF - Journal of Clinical Endocrinology and Metabolism
ER -
