Association of antepartum suicidal ideation during the third trimester with infant birth weight and gestational age at delivery

Bizu Gelaye; Amber Domingue; Fernanda Rebelo; Lauren E. Friedman; Chunfang Qiu; Sixto E. Sanchez; Gloria Larrabure-Torrealva; Michelle A. Williams

doi:10.1080/13548506.2018.1539235

Association of antepartum suicidal ideation during the third trimester with infant birth weight and gestational age at delivery

Bizu Gelaye, Amber Domingue, Fernanda Rebelo, Lauren E. Friedman, Chunfang Qiu, Sixto E. Sanchez, Gloria Larrabure-Torrealva, Michelle A. Williams

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Antepartum suicidal behaviors are a leading cause of maternal injury and death. Previous research has not investigated associations between antepartum suicidal ideation and perinatal complications. Our study objective was to evaluate the relationship of antepartum suicidal ideation with low infant birthweight, small for gestational age, and preterm birth. A cohort study was conducted among 1,108 women receiving prenatal care in Peru. Suicidal ideation was measured using the Patient Health Questionnaire-9 during pregnancy. Birth outcomes were extracted from medical records. Linear regressions and multivariable logistic regressions were used to estimate were used to investigate associations between suicidal ideation and pregnancy outcomes. The prevalence of suicidal ideation was 8.7%, preterm delivery was 5.7%, low birthweight was 4.4%, and small for gestational age was 3.4%. In an adjusted model, infant birthweight was 94.2 grams lower for mothers with antepartum suicidal ideation (95% CI: −183.0, −5.5, p = 0.037) compared with those without suicidal ideation. After adjusting for confounders including depression, participants with suicidal ideation had a nearly four-fold increased odds of delivering a small for gestational age infant (OR: 3.73; 95% CI: 1.59–8.74). These findings suggest suicidal ideation during pregnancy is associated with adverse perinatal outcomes, especially low infant birthweight.

Original language	English
Pages (from-to)	127-136
Number of pages	10
Journal	Psychology, Health and Medicine
Volume	24
Issue number	2
DOIs	https://doi.org/10.1080/13548506.2018.1539235
State	Published - 7 Feb 2019

Bibliographical note

Funding Information:
This research was supported by Roche Diagnostic Operations Inc. (project number 208617-5074547) and awards from the National Institutes of Health (NIH), National Institute of Minority Health and Health Disparities (T37-MD-001449) and the Eunice Kenney Shriver National Institute of Child Health and Human Development (R01-HD-059835). The NIH had no further role in study design; in the collection, analysis, and interpretation of data; in the writing of the report; and in the decision to submit the paper for publication. The authors wish to thank the dedicated staff members of Asociacion Civil Proyectos en Salud (PROESA), Peru, and Instituto Especializado Materno Perinatal, Peru, for their expert technical assistance with this research.

Funding Information:
This research was supported by Roche Diagnostic Operations Inc. (project number 208617-5074547) and awards from the National Institutes of Health (NIH), National Institute of Minority Health and Health Disparities (T37-MD-001449) and the Eunice Kenney Shriver National Institute of Child Health and Human Development (R01-HD-059835). The NIH had no further role in study design; in the collection, analysis, and interpretation of data; in the writing of the report; and in the decision to submit the paper for publication.

Publisher Copyright:
© 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group.

Keywords

birth weight
pregnancy
preterm birth
suicidal ideation

Access to Document

10.1080/13548506.2018.1539235

Cite this

@article{e274ef5b6997427db2ea0836fe50ee67,

title = "Association of antepartum suicidal ideation during the third trimester with infant birth weight and gestational age at delivery",

abstract = "Antepartum suicidal behaviors are a leading cause of maternal injury and death. Previous research has not investigated associations between antepartum suicidal ideation and perinatal complications. Our study objective was to evaluate the relationship of antepartum suicidal ideation with low infant birthweight, small for gestational age, and preterm birth. A cohort study was conducted among 1,108 women receiving prenatal care in Peru. Suicidal ideation was measured using the Patient Health Questionnaire-9 during pregnancy. Birth outcomes were extracted from medical records. Linear regressions and multivariable logistic regressions were used to estimate were used to investigate associations between suicidal ideation and pregnancy outcomes. The prevalence of suicidal ideation was 8.7%, preterm delivery was 5.7%, low birthweight was 4.4%, and small for gestational age was 3.4%. In an adjusted model, infant birthweight was 94.2 grams lower for mothers with antepartum suicidal ideation (95% CI: −183.0, −5.5, p = 0.037) compared with those without suicidal ideation. After adjusting for confounders including depression, participants with suicidal ideation had a nearly four-fold increased odds of delivering a small for gestational age infant (OR: 3.73; 95% CI: 1.59–8.74). These findings suggest suicidal ideation during pregnancy is associated with adverse perinatal outcomes, especially low infant birthweight.",

keywords = "birth weight, pregnancy, preterm birth, suicidal ideation",

author = "Bizu Gelaye and Amber Domingue and Fernanda Rebelo and Friedman, {Lauren E.} and Chunfang Qiu and Sanchez, {Sixto E.} and Gloria Larrabure-Torrealva and Williams, {Michelle A.}",

note = "Publisher Copyright: {\textcopyright} 2018, {\textcopyright} 2018 Informa UK Limited, trading as Taylor & Francis Group.",

year = "2019",

month = feb,

day = "7",

doi = "10.1080/13548506.2018.1539235",

language = "Ingl{\'e}s",

volume = "24",

pages = "127--136",

journal = "Psychology, Health and Medicine",

issn = "1354-8506",

publisher = "Routledge",

number = "2",

}

TY - JOUR

T1 - Association of antepartum suicidal ideation during the third trimester with infant birth weight and gestational age at delivery

AU - Gelaye, Bizu

AU - Domingue, Amber

AU - Rebelo, Fernanda

AU - Friedman, Lauren E.

AU - Qiu, Chunfang

AU - Sanchez, Sixto E.

AU - Larrabure-Torrealva, Gloria

AU - Williams, Michelle A.

PY - 2019/2/7

Y1 - 2019/2/7

N2 - Antepartum suicidal behaviors are a leading cause of maternal injury and death. Previous research has not investigated associations between antepartum suicidal ideation and perinatal complications. Our study objective was to evaluate the relationship of antepartum suicidal ideation with low infant birthweight, small for gestational age, and preterm birth. A cohort study was conducted among 1,108 women receiving prenatal care in Peru. Suicidal ideation was measured using the Patient Health Questionnaire-9 during pregnancy. Birth outcomes were extracted from medical records. Linear regressions and multivariable logistic regressions were used to estimate were used to investigate associations between suicidal ideation and pregnancy outcomes. The prevalence of suicidal ideation was 8.7%, preterm delivery was 5.7%, low birthweight was 4.4%, and small for gestational age was 3.4%. In an adjusted model, infant birthweight was 94.2 grams lower for mothers with antepartum suicidal ideation (95% CI: −183.0, −5.5, p = 0.037) compared with those without suicidal ideation. After adjusting for confounders including depression, participants with suicidal ideation had a nearly four-fold increased odds of delivering a small for gestational age infant (OR: 3.73; 95% CI: 1.59–8.74). These findings suggest suicidal ideation during pregnancy is associated with adverse perinatal outcomes, especially low infant birthweight.

AB - Antepartum suicidal behaviors are a leading cause of maternal injury and death. Previous research has not investigated associations between antepartum suicidal ideation and perinatal complications. Our study objective was to evaluate the relationship of antepartum suicidal ideation with low infant birthweight, small for gestational age, and preterm birth. A cohort study was conducted among 1,108 women receiving prenatal care in Peru. Suicidal ideation was measured using the Patient Health Questionnaire-9 during pregnancy. Birth outcomes were extracted from medical records. Linear regressions and multivariable logistic regressions were used to estimate were used to investigate associations between suicidal ideation and pregnancy outcomes. The prevalence of suicidal ideation was 8.7%, preterm delivery was 5.7%, low birthweight was 4.4%, and small for gestational age was 3.4%. In an adjusted model, infant birthweight was 94.2 grams lower for mothers with antepartum suicidal ideation (95% CI: −183.0, −5.5, p = 0.037) compared with those without suicidal ideation. After adjusting for confounders including depression, participants with suicidal ideation had a nearly four-fold increased odds of delivering a small for gestational age infant (OR: 3.73; 95% CI: 1.59–8.74). These findings suggest suicidal ideation during pregnancy is associated with adverse perinatal outcomes, especially low infant birthweight.

KW - birth weight

KW - pregnancy

KW - preterm birth

KW - suicidal ideation

UR - http://www.scopus.com/inward/record.url?scp=85055989429&partnerID=8YFLogxK

U2 - 10.1080/13548506.2018.1539235

DO - 10.1080/13548506.2018.1539235

M3 - Artículo

C2 - 30376725

AN - SCOPUS:85055989429

SN - 1354-8506

VL - 24

SP - 127

EP - 136

JO - Psychology, Health and Medicine

JF - Psychology, Health and Medicine

IS - 2

ER -

Association of antepartum suicidal ideation during the third trimester with infant birth weight and gestational age at delivery

Abstract

Bibliographical note

Keywords

Access to Document

Other files and links

Fingerprint

Cite this