Clinical and serological evidence of Toxocara infection in school children from Morrope district, Lambayeque, Peru

Yrma A. Espinoza, Pedro H. Huapaya, William H. Roldán, Susana Jiménez, Zhandra Arce, Elmer Lopez

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38 Scopus citations


The aim of this study was to estimate the frequency of human toxocariosis in a child population from Morrope district, Lambayeque, Peru. From October to December 2005, 182 school children (96 male and 86 female) were studied. Blood samples were collected for Toxocara ELISA-IgG test and hematological examination. Additionally, stool samples were collected for coproparasitological examination to check cross reactions. We found frequency of positives in 32.4% (59/182) with a significant higher proportion of positivity in male children (p < 0.00001). 71.2% of the children with positive serology (52 male and seven female), were between five and 10 years old, 77.96% had respiratory symptoms, 61.02% had ocular manifestations, 38.98% had hepatic symptoms, 38.98% had mild or moderate eosinophilia, signs statistically associated with seropositivity. 83.5% of studied population had some intestinal parasite, such as: Blastocystis hominis (53.3%), Giardia lamblia (31.3%), Entamoeba coli (29.1%), Entamoeba histolytica/E. dispar (1.1%), Hymenolepis nana (5.49%), and Ascaris lumbricoides (3.3%), but they had not any association with serology results. The ownership of dogs or/and cats were significantly associated with seropositivity to anti-Toxocara antibodies although the presence of such pets within the house was not. In conclusion, clinical and serological evidence of Toxocara infection exists in the studied population.

Original languageEnglish
Pages (from-to)101-105
Number of pages5
JournalRevista do Instituto de Medicina Tropical de Sao Paulo
Issue number2
StatePublished - Mar 2008
Externally publishedYes


  • Children
  • ELISA test
  • Frequency
  • Toxocariasis


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