Guía de práctica clínica para el tratamiento farmacológico inicial de nefritis lúpica en el Seguro Social del Perú (EsSalud)

Translated title of the contribution: Clinical practice guideline for the initial pharmacological treatment of lupus nephritis in the Peruvian Social Security (EsSalud)

Manuel Francisco Ugarte-Gil, Sergio Goicochea-Lugo, Milton A. Romero-Robles, Zhamanda N. Ortiz-Benique, Milko Ugaz-Zegarra, Juan E. Rodríguez-Mori, Martin Gomez-Lujan, Mirella Gutierrez-Vargas, Vidia Lumbe-Diaz, Luis Guevara-Rodríguez, Jesús De la Jara, Wilkerson Perez-Medina, Paolo Huamanyauri-Saavedra, Alvaro Hostia-Cardeña, Valentin Sottec-Roque, Miguel Vilca-Flores, Sandra Vargas-Marquez, Carolina J. Delgado-Flores, David García-Gomero, Gandy Dolores-MaldonadoAlvaro Taype-Rondan, Stefany Salvador-Salvador, Lourdes Carrera-Acosta

Research output: Contribution to journalArticlepeer-review

Abstract

Background: This article summarizes the clinical practice guideline (CPG) for the initial pharmacological treatment of lupus nephritis in the Social Security of Peru (EsSalud). Objective: To provide evidence-based clinical recommendations for initial pharmacological treatment of non-refractory adults with class I to V lupus nephritis in EsSalud. Material and Methods: A guideline development group (GDG) was formed, which included specialist physicians and methodologists, who formulated clinical questions. Systematic searches were conducted for systematic reviews and - when deemed relevant - primary studies in PubMed during 2021. Evidence was selected to answer each of the clinical questions posed. The certainty of evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology. In periodic working meetings, the GEG used the GRADE methodology to review the evidence and formulate recommendations. The CPG was reviewed by external experts before its approval. Results: The CPG addressed 6 clinical questions, divided into 2 topics: initial treatment of the induction and maintenance phase. Based on these questions, 11 recommendations were formulated (all conditional), 22 points of good clinical practice, and 2 flow charts. Conclusion: Evidence-based recommendations were issued for the management of patients with this pathology.

Translated title of the contributionClinical practice guideline for the initial pharmacological treatment of lupus nephritis in the Peruvian Social Security (EsSalud)
Original languageSpanish
Pages (from-to)523-534
Number of pages12
JournalRevista del Cuerpo Medico Hospital Nacional Almanzor Aguinaga Asenjo
Volume14
Issue number4
DOIs
StatePublished - Oct 2021
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2021 Revista del Cuerpo Médico del HNAAA. All rights reserved.

Fingerprint

Dive into the research topics of 'Clinical practice guideline for the initial pharmacological treatment of lupus nephritis in the Peruvian Social Security (EsSalud)'. Together they form a unique fingerprint.

Cite this