Abstract
Introduction: Dentin hypersensitivity is a common pathology, produced by exposed dental tubules. Objectives: The aim of this study was the evaluation of the effectiveness of experimental toothpaste based on nano-hydroxyapatite (nHAP) obtained from chicken eggshell in the obliteration of dentinal tubules (DTs). Material and methods: Toothpastes with different percentages of nHAP were formulated, including 3%, 7%, and 15% of nHAP, a commercial paste, and a toothpaste without nHAP. Assays were made using healthy premolar samples (n = 50). The pastes were applied and brushed for 7 days after a first erosive cycle, then a second erosive cycle was made at 15 days. Samples were analyzed using scanning electron microscopy and confocal Raman microscopy at three times: after the first erosive cycle (T0), after applications of the pastes (T7), and after the second erosive cycle (T15). Results: The quantitative analysis of the micrographs showed a significant difference between the experimental toothpastes with respect to the controls. Moreover, there was no statistically significant difference between the experimental toothpastes at time T7. By mineral concentration analysis, the 3%-nHAP toothpaste presented a significant difference against conventional toothpaste, when evaluating mineral concentration at 7 days. Conclusions: The experimental paste is effective in obliterating DTs at concentrations of 7 and 15%, in addition to being stable over time.
| Original language | English |
|---|---|
| Pages (from-to) | 147-154 |
| Number of pages | 8 |
| Journal | Journal of Stomatology |
| Volume | 75 |
| Issue number | 3 |
| DOIs | |
| State | Published - 2022 |
| Externally published | Yes |
Bibliographical note
Funding Information:This work was supported by the Escuela de Postgrado “Víctor Alzamora Castro” (Support fund for publication of articles by doctoral graduates 2021). J. A. Castañe-da-Vía recognizes a financial support of the Concytec – World Bank Project “Improvement and Expansion of the Services of the National System of Science, Technology, and Technological Innovation” 8682-PE, through its executing unit Fondecyt (Grant number: 08-2018). C.V. Landauro and J. Quispe are grateful to CONCYTEC, Peru for partial financial support through the Excellence Center Program.
Funding Information:
This work was supported by the Escuela de Postgrado “Víctor Alzamora Castro” (Support fund for publication of articles by doctoral graduates 2021). J. A. Castañeda-Vía recognizes a financial support of the Concytec - World Bank Project “Improvement and Expansion of the Services of the National System of Science, Technology, and Technological Innovation” 8682-PE, through its executing unit Fondecyt (Grant number: 08-2018). C.V. Landauro and J. Quispe are grateful to CONCYTEC, Peru for partial financial support through the Excellence Center Program.
Publisher Copyright:
© 2022 Termedia Publishing House Ltd.. All rights reserved.
Keywords
- durapatite
- eggshell
- hypersensitivity
- microscopy
- toothpastes