Objective: The purpose of this paper is to introduce the overarching study design of the South American Youth/Child Cardiovascular and Environmental (SAYCARE) study, which is an observational multicenter feasibility study held in seven South American cities: Buenos Aires (Argentina), Lima (Peru), Medellin (Colombia), Montevideo (Uruguay), Santiago (Chile), and São Paulo and Teresina (Brazil). Children and adolescents (3-17 years of age) were studied. Methods: The data management systems, quality assurance monitoring activities, standardized operating procedure manuals, and training and study management are addressed in this paper. Various quality controls to ensure the collection of valid and reliable data are also discussed. Results and Conclusions: Data were obtained from 237 preschoolers and schoolchildren and 258 adolescents during the validation phase measurements. The results of the SAYCARE study are expected to provide higher accuracy in the assessment of cardiovascular disease risk factors, including eating behaviors, body composition, physical activity, sedentary behaviors, lipid profiles and cardiovascular health biomarkers, oral health, social conditions, environmental factors and home environment, and their determinants in children and adolescents from ages 3 to 17 in seven South American cities.
Bibliographical noteFunding Information:
Funding agencies: ACFDeM received a postdoctoral scholarship from the National Counsel of Technological and Scientific Development (CNPq; proc. 313772/2014-2) and São Paulo Research Foundation (FAPESP; proc. 2014/13367-2 and 2015/14319-4). LAM was given a visiting professor scholarship from the São Paulo Research Foundation (FAPESP; proc. 2015/11406-3). CLMF received an advanced scientist scholarship from the National Counsel of Technological and Scientific Development (CNPq; proc. 304003/2014-0). HBC received a research grant from the São Paulo Research Foundation (2014/11468-6), Research Grant for Scientific Publication Paper (2017/15546-0), and an advanced scientist scholarship from the National Counsel of Technological and Scientific Development (CNPq; proc. 300951/2015-9). The South American Youth/Child Cardiovascular and Environmental (SAYCARE) study was supported mainly by the Brazilian Government from the National Counsel of Technological and Scientific Development (CNPq; proc. 471266/2013-2) and the São Paulo State Government from the São Paulo Research Foundation (FAPESP; proc. 2014/11468-6). The SAYCARE study was also cofunded by other agencies in other countries as follows: (1) the Collaborative Projects Fund (R.D. N 501-2015-INSN-DG-OEA) granted by the National Institute of Child Health, Lima, Peru; (2) the Sustainability Strategy at the University of Antioquia from 2014 to 2015, research group of social and economic determinants of health and nutrition, and Demography and Health Research Group at the University of Antioquia, Medellin, Colombia, and Interuniversity Services Corporation from the University of Antioquia; (3) the Secretary of University Extension and Student Welfare, University of Buenos Aires, Buenos Aires, Argentina; and (4) the European Regional Development Fund (MICINN-FEDER) to the Growth, Exercise, Nutrition and Development Research Group. Disclosure: The authors declared no conflict of interest. Author contributions: HBC, LAM, and ACFDeM designed this study. HBC, LAM, AMS and ACFDeM supervised the data analysis and interpretation. ACFDeM, GB, LIGZ, CAD, MIB, MLRS, FLTL, CLMF, LAM, and HBC contributed to the data collection. AE-R and PdeM-E contributed to data interpretation. All authors were involved in writing the paper and had final approval of the submitted and published versions. Additional Supporting Information may be found in the online version of this article. Received: 9 June 2017; Accepted: 14 December 2017; Published online 21 February 2018. doi:10.1002/oby.22117