Diphyllobothrium pacificum infection is seldom associated with megaloblastic anemia

Juan A. Jimenez, Silvia Rodriguez, Ricardo Gamboa, Lourdes Rodriguez, Hector H. Garcia

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Twenty cases of Dyphillobothrium pacificum (fish tapeworm) infections were prospectively studied to determine whether this tapeworm is associated with megaloblastic anemia, as commonly reported for D. latum infections. The most frequent symptoms were fatigue and mild abdominal pain, which were identified in approximately 66.6% of the 18 patients interviewed. Fourteen patients received treatment with niclosamide and all were cured. The other six patients spontaneously eliminated the tapeworms. One patient, who also had chronic diabetes and gastric atrophy, had low vitamin B12 levels and megaloblastic anemia. In all other patients, including three other patients with anemia, baseline vitamin B12 levels were in the reference range and did not significantly change when re-assessed three months later. Unlike D. latum, infection with D. pacificum is seldom associated with megaloblastic anemia or vitamin B12 deficit.

Original languageEnglish
Pages (from-to)897-901
Number of pages5
JournalAmerican Journal of Tropical Medicine and Hygiene
Issue number5
StatePublished - Nov 2012


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