Dried blood spots versus sera for detection of rubella virus-specific immunoglobulin M (IgM) and IgG in samples collected during a rubella outbreak in Peru

Rita F. Helfand, Cesar Cabezas, Emily Abernathy, Carlos Castillo-Solorzano, Ana Cecilia Ortiz, Hong Sun, Fernando Osores, Lucia Oliveira, Alvaro Whittembury, Myrna Charles, Jon Andrus, Joe Icenogle

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Most persons with rubella virus-specific immunoglobulin M (IgM)- or IgG-positive sera tested positive (98% [n = 178] and 99% [n = 221], respectively) using paired filter paper dried blood spot (DBS) samples, provided that DBS indeterminate results were called positive. For persons with IgM- or IgG-negative sera, 97% and 98%, respectively, were negative using DBS.

Original languageEnglish
Pages (from-to)1522-1525
Number of pages4
JournalClinical and Vaccine Immunology
Volume14
Issue number11
DOIs
StatePublished - Nov 2007

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