Efecto antitumoral del extracto acuoso de Bomarea cornigera (Alstroemeriaceae) en sarcomas inducidos en ratones

José Suárez, Christian Villanueva, Claudia Rodríguez, Karol Lavado, Melissa Barbieri, Luis Guzmán, Ricardo Alfaro, José Pino

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

© Facultad de Ciencias Biológicas UNMSM We investigated antitumor effect of aqueous extract of Bomarea cornigera. Swiss albino mice strain were inoculated with tumor cell line TG-180 for 15 days, after which they were separated into 5 groups (n= 5 per group). Cyclophosphamide was administered intraperitoneally (positive control), distilled water (negative control) and the aqueous extract at concentrations of 1X, 2X and 4X; the morbidity, mortality, weight and length of the sarcoma were assessed. We found an inhibitory effect of extract of B. cornigera in the development of solid tumor in mice where the TG-180 sarcoma was transplanted. The inhibition rates were 87.44 and 8.52% after 17 days of treatment, considering 1X dose (lowest) and 2X (intermediate), respectively. These results suggest that administration of aqueous extract of B. cornigera intraperitoneally may be useful as a cancer inhibitor.
Original languageAmerican English
Pages (from-to)385-388
Number of pages4
JournalRevista Peruana de Biologia
StatePublished - 1 Dec 2010

Fingerprint Dive into the research topics of 'Efecto antitumoral del extracto acuoso de Bomarea cornigera (Alstroemeriaceae) en sarcomas inducidos en ratones'. Together they form a unique fingerprint.

  • Cite this

    Suárez, J., Villanueva, C., Rodríguez, C., Lavado, K., Barbieri, M., Guzmán, L., Alfaro, R., & Pino, J. (2010). Efecto antitumoral del extracto acuoso de Bomarea cornigera (Alstroemeriaceae) en sarcomas inducidos en ratones. Revista Peruana de Biologia, 385-388.