© 2015, Instituto Nacional de Salud. All rights reserved. Variations in serum potassium (K+) and electrocardiographic changes at different infusion speeds of intravenous K+ were studied in dogs. Solutions of 20, 40, 60 and 80 mEq of K+ were infused in one hour to dogs with normal renal function and normal serum K+. Nine dogs were studied: three without prior hydration and six with previous hydration. Infusing 20 mEq / hour of K+ produced an increase in heart rate without changes in the electrocardiogram. With 40 mEq / hour there were changes in the “t” and “p” waves, and with 60 and 80 mEq / hour, alterations consistent with cardiac ischemia and ventricular tachycardia. Dogs without hydration had more obvious and fatal electrocardiographic changes. Doses of 20 mEq / hour of K + caused no morbidity or mortality in the animals studied. Higher doses showed various complications which depended on the hydration status of the animal, its urinary flow and potassium level.
|Original language||American English|
|Number of pages||7|
|Journal||Revista Peruana de Medicina Experimental y Salud Publica|
|State||Published - 1 Jan 2015|
Bravo-Zúñiga, J., Huapaya, J., Valencia, C., Bezada, S., Leon, C., Ferrandiz-Espadin, R., & Cieza, J. (2015). Effect of intravenous infusion of KCL on the electrocardiogram and serum potassium in dogs with normal renal function. Revista Peruana de Medicina Experimental y Salud Publica, 110-116.