Efectos de la variación en la presión de oxígeno ambiental sobre el movimiento dentario ortodóntico.

Translated title of the contribution: Effects of ambient oxygen pressure on orthodontic tooth movement.

Victor Chumpitaz-Cerrate, Lesly Chavez-Rimache, Elías Aguirre-Siancas, César Franco-Quino, Eliberto Ruiz-Ramirez, Victoria Caldas-Cueva

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To evaluate the effects of variation in ambient oxygen pressure on orthodontic tooth movement in guinea pigs. Material and Methods: Seventy-two guinea pigs randomly distributed into two groups (A and B) were evaluated in the study. All specimens were fitted with orthodontic appliances to distalize maxillary incisors. Group A was controlled under conditions of oxygen pressures at sea level (150 masl, 157 mm Hg) and Group B under conditions of oxygen pressures at altitude (3405 masl, 107 mm Hg). The clinical (distance between the distal-incisal angles of the maxillary incisors), biochemical (serum alkaline phosphatase), and histopathological characteristics (osteoblast and osteocyte count) were evaluated before placing the orthodontic devices and after 24 and 72 hours. Results: In the clinical evaluation, the distance between the distal-incisal angles of the maxillary incisors, on day one and three, was significantly higher in group B compared to group A (p=0.002 and p=0.001, respectively). In the biochemical evaluation, the level of serum alkaline phosphatase on the first and third days was significantly higher in group B compared to group A (p=0.001 and p=0.001, respectively). In the histopathological evaluation, the osteoblasts and osteocytes count on day one and three was significantly higher in group B compared to group A (p<0.05). Conclusion: Oxygen pressure at high altitude positively influenced orthodontic tooth movement in guinea pigs, improving its clinical, biochemical, and histopathological characteristics.

Translated title of the contributionEffects of ambient oxygen pressure on orthodontic tooth movement.
Original languageSpanish
JournalJournal of Oral Research
Volume10
Issue number6
DOIs
StatePublished - 31 Dec 2021
Externally publishedYes

Bibliographical note

Funding Information:
Conflict of interests: No authors have a conflict of interest. Ethics approval: study protocol approved by the research institute of the School of Dentistry of Universidad Nacional Mayor de San Marcos, Perú. Funding: Subsidized 160501011 (RAIS UNMSM). Authors’ contributions: Chumpitaz-Cerrate V: conception, design of the study and writing of the original draft. Aguirre-Siancas E: writing of the original draft. Franco-Quino C: writing of the original draft. E. Ruiz-Ramirez: writing of the original draft. Chavez-Rimache L: Analysis and interpretation of the data, writing of the original draft. Caldas-Cueva V: Bibliographic review. All authors participated in the execution of the study. Acknowledgements: Our most sincere thanks to the Universidad Nacional Mayor de San Marcos for providing us with financial support to carry out this research work.

Publisher Copyright:
© 2021, Universidad de Concepcion. All rights reserved.

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