Eficacia de la azitromicina asociada al RAR en periodontitis crónica: ensayo clínico, aleatorizado, controlado y triple ciego en grupos en paralelo

Translated title of the contribution: Efficacy of azithromycin associated with RAR in chronic periodontitis: Clinical trial, randomized, controlled, triple blind parallel groups

Pablo Millones-Gómez, Alberto Aguirre Aguilar

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Objective: To evaluate the efficacy of azithromycin associated with RAR in patients with chronic periodontitis. Material and methods: This parallel randomized, controlled, triple blind clinical trial was undertakne in the Stomatology Clinic of the Catholic University Los Angeles of Chimbote (Trujillo, Peru), between March 2015 and February 2017. The participants were 70 adult patients randomised in to 2 groups, designated by the letters A and B, each with 35 members. Each patient was evaluated periodontally before scaling and root planing and optimisation of hygiene techniques. Patients in group A, were prescribed antibiotic treatment with azithromycin 500 mg orally every 24 hours for 3 days. While group B were prescribed a placebo with the same physical characteristics as the antibiotic chosen. Patients were evaluated at 3, 4 and 5 months. The efficacy was evaluated using the Student t test to compare means, considering a level of significance for the values of P < .05. Results: It was found that both groups were able to improve probing depth and clinical adherence, however no statistically significant differences were found between them. Conclusion: Azithromycin associated with RAR is not effective as adjuvant therapy in patients with chronic periodontitis.

Translated title of the contributionEfficacy of azithromycin associated with RAR in chronic periodontitis: Clinical trial, randomized, controlled, triple blind parallel groups
Original languageSpanish
Pages (from-to)129-134
Number of pages6
JournalRevista Espanola de Cirugia Oral y Maxilofacial
Volume40
Issue number3
DOIs
StatePublished - 2018

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© 2017 SECOM. Published by Elsevier España, S.L.U.

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