Histopathological analysis of 108 intestine samples (103 grossly affected ileum and 5 jejunum) taken from Clostridium-induced neonatal alpaca (Vicugna pacos) enterotoxemia mortalities collected in the Departments of Arequipa, Puno and Cusco of southern Peru during the 2005-2008 birth seasons (January-March), revealed the presence of large numbers of both asexual and sexual stages of Eimeria macusaniensis in 33/108 (30.55%) of the samples with moderate to severe necrotized and/or hemorrhagic enteritis. It is proposed that damage to the mucosa produced by coccidial infections may facilitate overgrowth of Clostridium perfringens with toxin production leading to fatal enterotoxemia.
Bibliographical noteFunding Information:
This study was partially supported by San Marcos University, CONCYTEC, INCAGRO, FINCyT and the CONOPA Research Institute. Special Thanks to J. C. Wheeler for assistance writing the manuscript and to the many Veterinarians and alpaca breeders who collaborated so effectively in collecting the samples reported in this study.
Copyright 2010 Elsevier B.V., All rights reserved.
- Clostridium perfringens
- Eimeria macusaniensis
- Histopathology lesions