TY - JOUR
T1 - Enfermedad de hígado graso no alcohólico (EHGNA)
T2 - Revisión y puesta al día. Grupo de trabajo de la sociedad latinoamericana de gastroenterología hepatología y nutrición pediátrica (SLAGHNP)
AU - Quintero, Fernando Sarmiento
AU - Botero, Verónica
AU - Agostino, Daniel D.
AU - Carbajal, Laura Delgado
AU - Olivera, María Rita Dewaele
AU - Guzmán, Celina
AU - Játiva, Edgar
AU - Martin, Graciela Teresita
AU - Castro, Milton Mejía
AU - Paranza, Lourdes Ortiz
AU - Uego, María Cecilia Pabón
AU - Quintana, Luis Peña
AU - Quirós-Tejeira, Rubén E.
AU - Rodríguez, Nelson Ramírez
AU - Ramonet, Margarita
AU - Medina, Juan Rivera
AU - Sanabria, Marta
AU - Sánchez Franco, Claudia P.
AU - Valdiviezo, Lidia Patricia
AU - Galoppo, Cristina
N1 - Publisher Copyright:
© 2016, Sociedad Argentina de Gastroenterologia. All rights reserved.
Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2016
Y1 - 2016
N2 - Summary Along with obesity, non-alcoholic fatty liver disease, and its progression to esteatohepatitis, have become the most frequent liver disease among children and teenagers. Since cirrhosis could be an outcome of this condition, it is urgent to test for it in overweight and obese patients. Objectives. To compile in a single article strategies for clinical coaching and handling of children with this condition. On the basis of this revision, to promote research projects. Methods. SLAGHNP/LAPSGHAN, under responsibility and supervision of an editor/coordinator who chose contents and references with the best evidence, called its associates to perform this revision, after which edition and unification of the contents proposed. Results. The severity of EHGNA/ EHNA is established as a new infant liver disease and the lack of information on it in Latin America is noted unlike the United State, where its status as the most prevalent hepatopathy among children has been already established. Usefulness of blood chemistry tests and images is emphasized; although it has not been established when it should be recommended, it is clear liver biopsy is the gold standard for detecting the disease. Conclusions. It is important to start in Latin America research and follow-up programs on this disease, whose rapid progression will be continentwise a public health concern in the near future. A latin american register should be started under leadership of SLAGHNP/LAPSGHAN to establish this liver disease's epidemiology, establish a clinical diagnosis and choose adequate complimentary tests to confirm diagnosis.
AB - Summary Along with obesity, non-alcoholic fatty liver disease, and its progression to esteatohepatitis, have become the most frequent liver disease among children and teenagers. Since cirrhosis could be an outcome of this condition, it is urgent to test for it in overweight and obese patients. Objectives. To compile in a single article strategies for clinical coaching and handling of children with this condition. On the basis of this revision, to promote research projects. Methods. SLAGHNP/LAPSGHAN, under responsibility and supervision of an editor/coordinator who chose contents and references with the best evidence, called its associates to perform this revision, after which edition and unification of the contents proposed. Results. The severity of EHGNA/ EHNA is established as a new infant liver disease and the lack of information on it in Latin America is noted unlike the United State, where its status as the most prevalent hepatopathy among children has been already established. Usefulness of blood chemistry tests and images is emphasized; although it has not been established when it should be recommended, it is clear liver biopsy is the gold standard for detecting the disease. Conclusions. It is important to start in Latin America research and follow-up programs on this disease, whose rapid progression will be continentwise a public health concern in the near future. A latin american register should be started under leadership of SLAGHNP/LAPSGHAN to establish this liver disease's epidemiology, establish a clinical diagnosis and choose adequate complimentary tests to confirm diagnosis.
KW - Adolescentes
KW - Children
KW - Metabolic syndrome
KW - Non alcoholic fatty liver disease
KW - Non alcoholic steatohepatitis
UR - http://www.scopus.com/inward/record.url?scp=84991449523&partnerID=8YFLogxK
M3 - Artículo de revisión
AN - SCOPUS:84991449523
SN - 0300-9033
VL - 46
SP - 246
EP - 264
JO - Acta Gastroenterologica Latinoamericana
JF - Acta Gastroenterologica Latinoamericana
IS - 3
ER -