Epidemiology

Manuel F. Ugarte-Gil, Guillermo J. Pons-Estel, Graciela S. Alarcón

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

© 2016 Elsevier Inc. All rights reserved. Systemic lupus erythematosus (SLE) is a disease distributed worldwide that occurs in both genders and across racial/ethnic and age groups; however, higher rates are observed in adults, women, and non-Caucasians. Genetic, environmental, sociodemographic, and methodological issues are responsible for these differences and for the variable course and outcome of the disease. Non-Caucasians may have more severe disease with a higher risk for early mortality and damage accrual. Males also may have a more severe disease; however, a negative impact of male gender on lupus outcomes has not been firmly established. Childhood onset is associated with a more severe disease; however, it is not associated with higher damage or diminished survival. Finally, late-onset lupus is associated with a mild disease but with higher damage accrual and a diminished survival.
Original languageAmerican English
Title of host publicationSystemic Lupus Erythematosus: Basic, Applied and Clinical Aspects
Number of pages7
ISBN (Electronic)9780128020098, 9780128019177
DOIs
StatePublished - 1 Jan 2016
Externally publishedYes

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    Ugarte-Gil, M. F., Pons-Estel, G. J., & Alarcón, G. S. (2016). Epidemiology. In Systemic Lupus Erythematosus: Basic, Applied and Clinical Aspects https://doi.org/10.1016/B978-0-12-801917-7.00003-6