Etiología y factores de riesgo para un primer episodio de isquemia cerebral en adultos jóvenes

Translated title of the contribution: Etiology and risk factors for a first episode of cerebral isquemia in young adults

B. Tarazona, W. Ramos, J. Arce, J. Yarinsueca, S. Morales, G. Ronceros, C. Galarza, J. Pérez

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: To determinate the etiology and risk factors for a first episode of cerebral ischemia in young adults at three hospitals of Lima and Callao-Peru. Methods: Multicentric study carried out at three national hospitals in Lima. The sample included 30 patients with a first episode of stroke and 60 controls matched by age and sex 2:1 with the patients. Serum biochemistry studies, EKGs and echocardiograms were done. Etiologies were classified based on the classification of Baltimore-Washington Cooperative Young Stroke Study. Results: The most frequent etiologies were cardiac embolism and atherosclerotic valvular heart disease, which were 30% of the cases (9 patients) each one. Hypertriglyceridemia (p. = 0.014), valvular heart disease (p. = 0.001) and hormonal contraception/replacement therapy (p. = 0.002) were independent risk factors for a first episode of cerebral ischemia in peruvian young adults. Motor deficiency was the most frequent presentation (50.0%). Intracraneal hypertension and urinary tract infection were the most frequent complications during acute ischemia and mortality was raised up to 10%. Conclusions: The hypertriglyceridemia, valvular heart disease and the use of oral contraceptives are independent risk factors for a first episode of ischemia in young adults from three hospitals of Lima and Callao. The most frequent etiologies were cardiac embolism and atheroesclerotic valvular heart disease.

Translated title of the contributionEtiology and risk factors for a first episode of cerebral isquemia in young adults
Original languageSpanish
Pages (from-to)470-477
Number of pages8
JournalNeurologia
Volume25
Issue number8
DOIs
StatePublished - Oct 2010

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