Evaluation of A PCR-Based Universal Heteroduplex Generator Assay As A Tool for Rapid Detection of Multidrug-Resistant Mycobacterium tuberculosis in Peru

Holger Mayta, Robert H. Gilman, Fanny Arenas, Teresa Valencia, Luz Caviedes, Sonia H. Montenegro, Eduardo Ticona, Jaime Ortiz, Rosa Chumpitaz, Carlton A. Evans, Diana L. Williams

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Multidrug-resistant tuberculosis is an increasing health problem worldwide, especially in developing countries. The PCR-UHG-Rif assay, which detects mutations within the rpoB gene associated with rifampin resistance, was evaluated for its ability and reliability to detect and identify drug-resistant Mycobacterium tuberculosis in a developing country where tuberculosis is highly endemic.
Original languageAmerican English
Pages (from-to)5774-5777
Number of pages4
JournalJournal of Clinical Microbiology
DOIs
StatePublished - 1 Dec 2003
Externally publishedYes

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    Mayta, H., Gilman, R. H., Arenas, F., Valencia, T., Caviedes, L., Montenegro, S. H., Ticona, E., Ortiz, J., Chumpitaz, R., Evans, C. A., & Williams, D. L. (2003). Evaluation of A PCR-Based Universal Heteroduplex Generator Assay As A Tool for Rapid Detection of Multidrug-Resistant Mycobacterium tuberculosis in Peru. Journal of Clinical Microbiology, 5774-5777. https://doi.org/10.1128/JCM.41.12.5774-5777.2003