Failure of one-day praziquantel treatment in patients with multiple neurocysticercosis lesions

E. Javier Pretell; Héctor H. García; Robert H. Gilman; Herbert Saavedra; Manuel Martinez; S. Rodriguez; C. Padilla; M. Porras; A. E. Gonzalez; M. Verastegui; C. Evans; V. C.W. Tsang

doi:10.1016/S0303-8467(01)00137-8

Failure of one-day praziquantel treatment in patients with multiple neurocysticercosis lesions

E. Javier Pretell, Héctor H. García, Robert H. Gilman, Herbert Saavedra, Manuel Martinez, S. Rodriguez, C. Padilla, M. Porras, A. E. Gonzalez, M. Verastegui, C. Evans, V. C.W. Tsang

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Abstract

A recently described one-day regimen of praziquantel (PZQ) therapy for neurocysticercosis (NCC), three doses of 25 mg/k given at 2 h intervals, was applied in eight patients with viable NCC cysts without any evidence of inflammation. Resolution of lesions in computed tomography (CT) was observed in all five patients with a single cyst, whereas all cysts survived in three patients with multiple brain parasites. One-day praziquantel is a good regimen for patients with a single viable brain cysticercus but is poorly effective for multiple cysts. Copyright © 2001 Elsevier Science B.V.

Original language	American English
Pages (from-to)	175-177
Number of pages	3
Journal	Clinical Neurology and Neurosurgery
DOIs	https://doi.org/10.1016/S0303-8467(01)00137-8
State	Published - 1 Jan 2001

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Pretell, E. J., García, H. H., Gilman, R. H., Saavedra, H., Martinez, M., Rodriguez, S., Padilla, C., Porras, M., Gonzalez, A. E., Verastegui, M., Evans, C., & Tsang, V. C. W. (2001). Failure of one-day praziquantel treatment in patients with multiple neurocysticercosis lesions. Clinical Neurology and Neurosurgery, 175-177. https://doi.org/10.1016/S0303-8467(01)00137-8

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abstract = "A recently described one-day regimen of praziquantel (PZQ) therapy for neurocysticercosis (NCC), three doses of 25 mg/k given at 2 h intervals, was applied in eight patients with viable NCC cysts without any evidence of inflammation. Resolution of lesions in computed tomography (CT) was observed in all five patients with a single cyst, whereas all cysts survived in three patients with multiple brain parasites. One-day praziquantel is a good regimen for patients with a single viable brain cysticercus but is poorly effective for multiple cysts. Copyright {\textcopyright} 2001 Elsevier Science B.V.",

author = "Pretell, {E. Javier} and Garc{\'i}a, {H{\'e}ctor H.} and Gilman, {Robert H.} and Herbert Saavedra and Manuel Martinez and S. Rodriguez and C. Padilla and M. Porras and Gonzalez, {A. E.} and M. Verastegui and C. Evans and Tsang, {V. C.W.}",

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doi = "10.1016/S0303-8467(01)00137-8",

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AU - Pretell, E. Javier

AU - García, Héctor H.

AU - Gilman, Robert H.

AU - Saavedra, Herbert

AU - Martinez, Manuel

AU - Rodriguez, S.

AU - Padilla, C.

AU - Porras, M.

AU - Gonzalez, A. E.

AU - Verastegui, M.

AU - Evans, C.

AU - Tsang, V. C.W.

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N2 - A recently described one-day regimen of praziquantel (PZQ) therapy for neurocysticercosis (NCC), three doses of 25 mg/k given at 2 h intervals, was applied in eight patients with viable NCC cysts without any evidence of inflammation. Resolution of lesions in computed tomography (CT) was observed in all five patients with a single cyst, whereas all cysts survived in three patients with multiple brain parasites. One-day praziquantel is a good regimen for patients with a single viable brain cysticercus but is poorly effective for multiple cysts. Copyright © 2001 Elsevier Science B.V.

AB - A recently described one-day regimen of praziquantel (PZQ) therapy for neurocysticercosis (NCC), three doses of 25 mg/k given at 2 h intervals, was applied in eight patients with viable NCC cysts without any evidence of inflammation. Resolution of lesions in computed tomography (CT) was observed in all five patients with a single cyst, whereas all cysts survived in three patients with multiple brain parasites. One-day praziquantel is a good regimen for patients with a single viable brain cysticercus but is poorly effective for multiple cysts. Copyright © 2001 Elsevier Science B.V.

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Failure of one-day praziquantel treatment in patients with multiple neurocysticercosis lesions

Abstract

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