Failure of one-day praziquantel treatment in patients with multiple neurocysticercosis lesions

E. Javier Pretell, Héctor H. García, Robert H. Gilman, Herbert Saavedra, Manuel Martinez, S. Rodriguez, C. Padilla, M. Porras, A. E. Gonzalez, M. Verastegui, C. Evans, V. C.W. Tsang

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25 Scopus citations

Abstract

A recently described one-day regimen of praziquantel (PZQ) therapy for neurocysticercosis (NCC), three doses of 25 mg/k given at 2 h intervals, was applied in eight patients with viable NCC cysts without any evidence of inflammation. Resolution of lesions in computed tomography (CT) was observed in all five patients with a single cyst, whereas all cysts survived in three patients with multiple brain parasites. One-day praziquantel is a good regimen for patients with a single viable brain cysticercus but is poorly effective for multiple cysts. Copyright © 2001 Elsevier Science B.V.
Original languageAmerican English
Pages (from-to)175-177
Number of pages3
JournalClinical Neurology and Neurosurgery
DOIs
StatePublished - 1 Jan 2001

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