Field evaluation of a coproantigen enzyme-linked immunosorbent assay for diagnosis of canine echinococcosis in a rural Andean village in Peru

Luis Lopera, Pedro L. Moro, Amanda Chavez, Glicerio Montes, Armando Gonzales, Robert H. Gilman

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

One hundred and six dogs (61 males and 45 females) were examined for Echinococcus granulosus infection in a farming cooperative in the central highlands of Peru during November 1998. Canine echinococcosis was diagnosed using direct microscopic examinations of purged feces following arecoline purging and a coproantigen-detection enzyme-linked immunosorbent assay (ELISA) for E. granulosus. Mean age was 2 years with a range of 3 months to 9 years. The overall prevalence of canine echinococcosis using the ELISA test was 79% (84/106). Seventy-four dogs were successfully purged with arecoline. The frequency of canine echinococcosis was 82 (61/74) and 34% (25/74) by the coproantigen ELISA test and arecoline purging, respectively. The sensitivity and specificity of the coproantigen ELISA test was 88 and 95%, respectively. We found this assay to be especially advantageous in remote geographical areas. In future control programs against echinococcosis in Peru and other areas where E. granulosus is endemic the coproantigen ELISA should be used for the surveillance of the dog population.

Original languageEnglish
Pages (from-to)37-42
Number of pages6
JournalVeterinary Parasitology
Volume117
Issue number1-2
DOIs
StatePublished - 3 Nov 2003

Bibliographical note

Funding Information:
This study was funded by Consejo Nacional de Ciencia y Tecnologı́a (CONCYTEC). We wish to thank Dr. Peter Schantz for manuscript review and the people and authorities of the farming cooperative of Tupac Amaru in Junin, Peru.

Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.

Keywords

  • Coproantigen ELISA
  • Diagnosis
  • Dog
  • Echinococcus granulosus
  • Peru

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