First report of Trypanosoma cruzi infection in salivary gland of bats from the Peruvian Amazon

Fredy E. Villena, Luis A. Gomez-Puerta, Erik J. Jhonston, O. Melisa Del Alcazar, Jorge L. Maguiña, Christian Albujar, V. Alberto Laguna-Torres, Sergio E. Recuenco, Sarah Blythe Ballard, Julia S. Ampuero

Research output: Contribution to journalArticle

Abstract

© Copyright 2018 by The American Society of Tropical Medicine and Hygiene. Inthe Americas, 8 million people are infected with Chagas disease, and anad ditional 90 million people are at risk for infection. Little is known about the role bats play in the sylvatic transmission cycle of Trypanosoma cruzi, the parasite causing Chagas disease. Here, wecaptured batsinthe villages of Palmiche, Pachacutec, Nuevo San Martin, and Mayuriaga located in the Datem del Marañon Province in Loreto, Peru. Venous blood samples were collected by cardiac puncture or from the upper extremities, and trypanosomatids were identified by microscopy and molecularly. We collected blood samples from 121 bats on filter paper for molecular studies and 111 slides for microscopic examination of thin and thick blood smears from 16 different bat species. The prevalence of trypanosomatids in all bats species was 34.7% (42/121) and the prevalence of T. cruzi was 4.1% (5/121). In hematophagous bat species, the prevalence of trypanosomatids and T. cruzi was 36.9% (27/73) and 2.7% (2/73), respectively. In non-hematophagous bats, the prevalences of trypanosomatids and T. cruzi were 31.2% (15/48) and 6.2% (3/48), respectively. Also, we confirm the presence of T. cruzi in salivary glands of hematophagous bats Diaemus youngi. These results suggest a sylvatic cycle of trypa-nosomatid transmission in which bats may harbor infectious T. cruzi parasites that could be transmitted to humans via hematophagous bat bites or salivary contamination by non-hematophagous bats of vegetables consumed by humans.
Original languageAmerican English
Pages (from-to)723-728
Number of pages6
JournalAmerican Journal of Tropical Medicine and Hygiene
DOIs
StatePublished - 1 Jan 2018

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    Villena, F. E., Gomez-Puerta, L. A., Jhonston, E. J., Del Alcazar, O. M., Maguiña, J. L., Albujar, C., Laguna-Torres, V. A., Recuenco, S. E., Ballard, S. B., & Ampuero, J. S. (2018). First report of Trypanosoma cruzi infection in salivary gland of bats from the Peruvian Amazon. American Journal of Tropical Medicine and Hygiene, 723-728. https://doi.org/10.4269/ajtmh.17-0816