Glioblastoma of pineal region: report of four cases and literature review

Enrique Orrego, Sandro Casavilca, Pamela Garcia-Corrochano, Sugey Rojas-Meza, Miluska Castillo, Carlos A. Castaneda

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


We report four cases of glioblastoma in the pineal region. The patients presented a severe headache and vomiting. Brain imaging showed a heterogeneously enhanced tumor in the pineal region with obstructive hydrocephalus. Case 3 developed a subependymal dissemination. The patient went to ventricular-peritoneal shunt and subtotal or total resection and radiotherapy with/without chemotherapy. Cases 1 and 2 received radiation and died 8 and 11 later months. Cases 3 and 4 completed radiotherapy and chemotherapy, and survived 28 and 31 months after the initial diagnosis. Glioblastoma in the pineal region carry a poor prognosis and require neurooncology teams.

Original languageEnglish
Pages (from-to)251-259
Number of pages9
JournalCNS oncology
Issue number4
StatePublished - 1 Oct 2017
Externally publishedYes


  • brain tumor
  • glioblastoma
  • pineal


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