Helicobacter pylori detected in tap water of peruvian patients with gastric cancer

Miluska Castillo, Luis A. Bernabe, Carlos A. Castaneda, Ivan Chavez, Eloy Ruiz, Fernando Barreda, Daniel Valdivia, Nancy Suarez, Jais Nieves, Emmanuel Dias-Neto, Kevin F. Boehnke, Maria P. Landa-Baella, Paola Montenegro

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Objective: To evaluate the correlation between the presence of H. pylori in paired samples of tap water and gastric cancer (GC) lesion in Lima city (Peru). Material and methods: Gastric tissue and tap-water samples were prospectively collected from 82 Gastric Cancer who lived in Lima. HspA and ureA genes were evaluated by qPCR in the samples. Results: The median age of patients with GC was 63 years, 52.4% were men and stage-II in 36.6%. A home-living time> 10 years was reported in 84.1% of patients. Boiling water treatment was indicated in 85.4% of cases. H. pylori was detected in 69.5% of gastric tissues and in 12.2% of analyzed tap-water. There was no differences in gastric infection rates among those with or without water contamination (70% vs. 69.4%, p=0.971). Conclusion & Impact: H. pylori was found in tap-water samples, however, detection rates were lower than in gastric cancer samples. Other sources of infection transmission should be investigated.

Original languageEnglish
Pages (from-to)3193-3196
Number of pages4
JournalAsian Pacific Journal of Cancer Prevention
Volume20
Issue number11
DOIs
StatePublished - 2019

Bibliographical note

Publisher Copyright:
© 2019, Asian Pacific Organization for Cancer Prevention.

Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.

Keywords

  • Cancer gastric
  • Helicobacter pylori
  • HspA
  • Tap-water
  • UreA

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