Hepatitis B in a highly active prostitute population: Evidence for a low risk of chronic antigenemia

Kenneth C. Hyams, Irving A. Phillips, Abelardo Tejada, Olga Li, Pilar Hermoza, Francisco Lopez, Pilar Alva, Gloria Chauca, Sara Sanchez, F. Stephen Wignall

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Abstract

The epidemiology of hepatitis B in female prostitutes was studied in a cross-sectional survey of 467 prostitutes and 510 control prenatal clinic patients from Lima and Iquitos, Peru. Prostitutes reported a mean of 8.8 ± 6.7 years of active prostitution and a mean of 205 ± 137 sexual contacts in the month prior to the study. Hepatitis B surface antigen (HBsAg) was found in comparable percentages of prostitutes (1.7%) and controls (0.8%; P =.305). In contrast, seropositivity for both antigen and antibody markers (HBsAg, anti-HBs, or anti-hepatitis Bcore) was found in a significantly higher percentage of prostitutes than controls (67.0% vs. 10.0%; P <.0001). By multivariate analysis, both prostitution (odds ratio [OR] 14.6) and the number of years of exposure as a prostitute (OR 3.2 for 10 years of exposure at age 35 years) were significantly associated with seropositivity for hepatitis B markers when adjusted for age. In this study, the prevalence of HBsAg was not substantially increased in highly active female prostitutes compared with the general population, even though hepatitis B transmission was greatly increased. These data suggest that in adult women with a high level of hepatitis B infection, hepatitis B antigenemia may not persist as frequently as previously indicated in studies of other populations. © 1990, by The University of Chicago.
Original languageAmerican English
Pages (from-to)295-298
Number of pages4
JournalJournal of Infectious Diseases
DOIs
StatePublished - 1 Jan 1990

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    Hyams, K. C., Phillips, I. A., Tejada, A., Li, O., Hermoza, P., Lopez, F., Alva, P., Chauca, G., Sanchez, S., & Wignall, F. S. (1990). Hepatitis B in a highly active prostitute population: Evidence for a low risk of chronic antigenemia. Journal of Infectious Diseases, 295-298. https://doi.org/10.1093/infdis/162.2.295