Hyperendemic human and porcine Taenia solium infection in Perú

Héctor H. García, Robert H. Gilman, Armando E. Gonzalez, Manuela Verastegui, Silvia Rodriguez, Cesar Gavidia, Victor C.W. Tsang, Nestor Falcon, Andres G. Lescano, Lawrence H. Moulton, Teresa Bernal, Marco Tovar, H. Mayta, J. Jimenez, P. Castillo, M. Martinez, C. A.W. Evans

Research output: Contribution to journalArticle

111 Scopus citations

Abstract

The prevalence and characteristics of human taeniasis/cysticercosis and porcine cysticercosis were assessed in an endemic area of the Peruvian highlands. Individuals from 10 communities had stool examinations (N = 2,951) and serologic testing for Taenia solium antibodies (N = 2,583). The total porcine population present (N = 703) was also examined by serology. Cysticercosis is hyperendemic in this area and is associated with an important number of seizure cases. Human seroprevalence by village ranged from 7.1-26.9% (mean, 13.9%). Seroprevalence was higher among individuals with a history of seizures but not in those reporting a history of headache or intestinal taeniasis. Prevalence of taeniasis ranged from 0-6.7% (median, 2.5%). Coproantigen detection found 2.4 times more taeniasis cases than did microscopy (direct and after concentration). Age distribution for taeniasis showed a peak at younger ages than for seroprevalence. Porcine seroprevalence ranged from 42-75%. Random effects logistic regression models for human seropositivity demonstrated both in-house clustering of cases and a large increase in risk associated with a tapeworm carrier in the house. Besides confirming the close relationship between taeniasis and cysticercosis cases, this large-scale field study demonstrated early age of tapeworm and cysticercosis infections in humans, and short duration of taeniasis infections.
Original languageAmerican English
Pages (from-to)268-275
Number of pages8
JournalAmerican Journal of Tropical Medicine and Hygiene
StatePublished - 1 Mar 2003

Fingerprint Dive into the research topics of 'Hyperendemic human and porcine Taenia solium infection in Perú'. Together they form a unique fingerprint.

  • Cite this

    García, H. H., Gilman, R. H., Gonzalez, A. E., Verastegui, M., Rodriguez, S., Gavidia, C., Tsang, V. C. W., Falcon, N., Lescano, A. G., Moulton, L. H., Bernal, T., Tovar, M., Mayta, H., Jimenez, J., Castillo, P., Martinez, M., & Evans, C. A. W. (2003). Hyperendemic human and porcine Taenia solium infection in Perú. American Journal of Tropical Medicine and Hygiene, 268-275.