Lipid/particle assemblies based on maltodextrin-gum arabic core as bio-carriers

Joana F.P.S. Gomes; Sandra Rocha; Maria do Carmo Pereira; Ivone Peres; Susana Moreno; José Toca-Herrera; Manuel A.N. Coelho

doi:10.1016/j.colsurfb.2009.12.004

Lipid/particle assemblies based on maltodextrin-gum arabic core as bio-carriers

Joana F.P.S. Gomes, Sandra Rocha, Maria do Carmo Pereira, Ivone Peres, Susana Moreno, José Toca-Herrera, Manuel A.N. Coelho

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

A novel system to carry and protect epigallocatechin gallate (EGCG), an antioxidant from the green tea, is reported. The system consists of maltodextrin and gum arabic nanoparticles coated with egg-yolk l-α-phosphatidylcholine (Egg-PC)/stearylamine (SA) bilayers. In this study, the polysaccharide core was produced by homogenization followed by spray-drying. The lipid coating was performed by the lipid film hydration method. The polysaccharide core revealed negative zeta potential, which changed to opposite signs after lipid coating. The presence of lipid layers was evidenced by cryogenic-transmission (cryo-TEM) and scanning (cryo-SEM) electron microscopy studies. An increase in size was observed after lipid coating as determined by dynamic light scattering (DLS). Atomic force microscopy (AFM) demonstrated that the polysaccharide core provides high resistance to mechanical strength. The lipid/particle assemblies show high retention efficiency of EGCG at physiological pH, opening the possibility of their use for delivery and controlled release of tea catechins.

Original language	English
Pages (from-to)	449-455
Number of pages	7
Journal	Colloids and Surfaces B: Biointerfaces
Volume	76
Issue number	2
DOIs	https://doi.org/10.1016/j.colsurfb.2009.12.004
State	Published - 1 Apr 2010
Externally published	Yes

Bibliographical note

Funding Information:
The authors thank David Gil Carton from CIC bioGUNE (Bilbao, Spain) for cryo-TEM measurements. Financial support was provided by the QREN project 1570 – BioCaps and FCT research project PTDC/BIO/69359/2006 and the integrate action AAII-HP2008-081.

Keywords

Carbohydrate nanoparticles
Catechins
Delivery systems
Lipid coating

Access to Document

10.1016/j.colsurfb.2009.12.004

Cite this

@article{3a6a02971425413faa67875b90a1c6eb,

title = "Lipid/particle assemblies based on maltodextrin-gum arabic core as bio-carriers",

abstract = "A novel system to carry and protect epigallocatechin gallate (EGCG), an antioxidant from the green tea, is reported. The system consists of maltodextrin and gum arabic nanoparticles coated with egg-yolk l-α-phosphatidylcholine (Egg-PC)/stearylamine (SA) bilayers. In this study, the polysaccharide core was produced by homogenization followed by spray-drying. The lipid coating was performed by the lipid film hydration method. The polysaccharide core revealed negative zeta potential, which changed to opposite signs after lipid coating. The presence of lipid layers was evidenced by cryogenic-transmission (cryo-TEM) and scanning (cryo-SEM) electron microscopy studies. An increase in size was observed after lipid coating as determined by dynamic light scattering (DLS). Atomic force microscopy (AFM) demonstrated that the polysaccharide core provides high resistance to mechanical strength. The lipid/particle assemblies show high retention efficiency of EGCG at physiological pH, opening the possibility of their use for delivery and controlled release of tea catechins.",

keywords = "Carbohydrate nanoparticles, Catechins, Delivery systems, Lipid coating",

author = "Gomes, {Joana F.P.S.} and Sandra Rocha and Pereira, {Maria do Carmo} and Ivone Peres and Susana Moreno and Jos{\'e} Toca-Herrera and Coelho, {Manuel A.N.}",

note = "Funding Information: The authors thank David Gil Carton from CIC bioGUNE (Bilbao, Spain) for cryo-TEM measurements. Financial support was provided by the QREN project 1570 – BioCaps and FCT research project PTDC/BIO/69359/2006 and the integrate action AAII-HP2008-081.",

year = "2010",

month = apr,

day = "1",

doi = "10.1016/j.colsurfb.2009.12.004",

language = "Ingl{\'e}s",

volume = "76",

pages = "449--455",

journal = "Colloids and Surfaces B: Biointerfaces",

issn = "0927-7765",

publisher = "Elsevier B.V.",

number = "2",

}

TY - JOUR

T1 - Lipid/particle assemblies based on maltodextrin-gum arabic core as bio-carriers

AU - Gomes, Joana F.P.S.

AU - Rocha, Sandra

AU - Pereira, Maria do Carmo

AU - Peres, Ivone

AU - Moreno, Susana

AU - Toca-Herrera, José

AU - Coelho, Manuel A.N.

N1 - Funding Information: The authors thank David Gil Carton from CIC bioGUNE (Bilbao, Spain) for cryo-TEM measurements. Financial support was provided by the QREN project 1570 – BioCaps and FCT research project PTDC/BIO/69359/2006 and the integrate action AAII-HP2008-081.

PY - 2010/4/1

Y1 - 2010/4/1

N2 - A novel system to carry and protect epigallocatechin gallate (EGCG), an antioxidant from the green tea, is reported. The system consists of maltodextrin and gum arabic nanoparticles coated with egg-yolk l-α-phosphatidylcholine (Egg-PC)/stearylamine (SA) bilayers. In this study, the polysaccharide core was produced by homogenization followed by spray-drying. The lipid coating was performed by the lipid film hydration method. The polysaccharide core revealed negative zeta potential, which changed to opposite signs after lipid coating. The presence of lipid layers was evidenced by cryogenic-transmission (cryo-TEM) and scanning (cryo-SEM) electron microscopy studies. An increase in size was observed after lipid coating as determined by dynamic light scattering (DLS). Atomic force microscopy (AFM) demonstrated that the polysaccharide core provides high resistance to mechanical strength. The lipid/particle assemblies show high retention efficiency of EGCG at physiological pH, opening the possibility of their use for delivery and controlled release of tea catechins.

AB - A novel system to carry and protect epigallocatechin gallate (EGCG), an antioxidant from the green tea, is reported. The system consists of maltodextrin and gum arabic nanoparticles coated with egg-yolk l-α-phosphatidylcholine (Egg-PC)/stearylamine (SA) bilayers. In this study, the polysaccharide core was produced by homogenization followed by spray-drying. The lipid coating was performed by the lipid film hydration method. The polysaccharide core revealed negative zeta potential, which changed to opposite signs after lipid coating. The presence of lipid layers was evidenced by cryogenic-transmission (cryo-TEM) and scanning (cryo-SEM) electron microscopy studies. An increase in size was observed after lipid coating as determined by dynamic light scattering (DLS). Atomic force microscopy (AFM) demonstrated that the polysaccharide core provides high resistance to mechanical strength. The lipid/particle assemblies show high retention efficiency of EGCG at physiological pH, opening the possibility of their use for delivery and controlled release of tea catechins.

KW - Carbohydrate nanoparticles

KW - Catechins

KW - Delivery systems

KW - Lipid coating

UR - http://www.scopus.com/inward/record.url?scp=75949099005&partnerID=8YFLogxK

U2 - 10.1016/j.colsurfb.2009.12.004

DO - 10.1016/j.colsurfb.2009.12.004

M3 - Artículo

C2 - 20060275

AN - SCOPUS:75949099005

SN - 0927-7765

VL - 76

SP - 449

EP - 455

JO - Colloids and Surfaces B: Biointerfaces

JF - Colloids and Surfaces B: Biointerfaces

IS - 2

ER -

Lipid/particle assemblies based on maltodextrin-gum arabic core as bio-carriers

Abstract

Bibliographical note

Keywords

Access to Document

Other files and links

Fingerprint

Cite this