Markers of plasmid resistance to qnr quinolones in clinical isolates of ctx-m beta-lactamases-producing enterobacteria in lima, peru

Lesdyth Jessica Toribio Arias, Carlos Raúl Sevilla Andrade, Edgar Gonzales-Escalante

Research output: Contribution to journalArticle

Abstract

© 2019, Instituto Nacional de Salud. All rights reserved. Aimed at reporting markers of plasmid resistance to qnr quinolones in clinical isolates of CTX-M beta-lactamase-producing enterobacteria, a descriptive study was conducted with isolates from the strain repository of TO-06/09 project of the National Children´s Health Institute. 138 isolates were recovered. Antimicrobial susceptibility was determined by the diffusion disk method, and gene identification by polymerase chain reaction. Of the 138 isolates, 67 (48.5%) were genotypically positive for qnr proteins; of these, 38 (56.7%) had qnrB determinants and 48 (71.6%) had qnrS determinants. No isolate presented qnrA determinants. qnr determinants were detected in isolates containing CTX-M beta-lactamases in a non-exposed population.
Original languageAmerican English
Pages (from-to)265-269
Number of pages5
JournalRevista Peruana de Medicina Experimental y Salud Publica
DOIs
StatePublished - 1 Jun 2019

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