Molecular biology of exocrine pancreatic cancer

José Luis Soto, Víctor Manuel Barbera, Miguel Saceda, Alfredo Carrato

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations

Abstract

Exocrine pancreatic cancer is one of the neoplasias with a worse prognosis, with conventional treatments having little impact on disease outcome. Research and genomic high-throughput technology is continuously expanding our knowledge of pancreas cancer biology. Characterization of genetic and epigenetic alterations in pancreatic tumors has allowed a better understanding of the progression model of the disease at the molecular level. The development of new therapeutic approaches with target-oriented agents is been tested in the preclinical and clinical settings. This review updates the current available data on pancreatic cancer molecular biology.

Original languageEnglish
Pages (from-to)306-312
Number of pages7
JournalClinical and Translational Oncology
Volume8
Issue number5
DOIs
StatePublished - 2006

Keywords

  • Genetic alterations
  • Molecular biology
  • New drugs
  • Pancreatic cancer

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