Phylogenomics reveals multiple introductions and early spread of SARS-CoV-2 into Peru

Eduardo Juscamayta-López; Dennis Carhuaricra; David Tarazona; Faviola Valdivia; Nancy Rojas; Lenin Maturrano; Ronnie Gavilán

doi:10.1002/jmv.27167

Phylogenomics reveals multiple introductions and early spread of SARS-CoV-2 into Peru

Eduardo Juscamayta-López, Dennis Carhuaricra, David Tarazona, Faviola Valdivia, Nancy Rojas, Lenin Maturrano, Ronnie Gavilán

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Peru has become one of the countries with the highest mortality rates from the current coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To investigate early transmission events and the genomic diversity of SARS-CoV-2 isolates circulating in Peru in the early COVID-19 pandemic, we analyzed 3472 viral genomes, of which 149 were from Peru. Phylogenomic analysis revealed multiple and independent introductions of the virus likely from Europe and Asia and a high diversity of genetic lineages circulating in Peru. In addition, we found evidence for community-driven transmission of SARS-CoV-2 as suggested by clusters of related viruses found in patients living in different regions of Peru.

Original language	English
Pages (from-to)	5961-5968
Number of pages	8
Journal	Journal of Medical Virology
Volume	93
Issue number	10
DOIs	https://doi.org/10.1002/jmv.27167
State	Published - Oct 2021
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2021 Wiley Periodicals LLC

Keywords

SARS-CoV-2
evolution
molecular epidemiology
phylogenomics
transmission
whole-genome sequencing

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/jmv.27167

Cite this

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abstract = "Peru has become one of the countries with the highest mortality rates from the current coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To investigate early transmission events and the genomic diversity of SARS-CoV-2 isolates circulating in Peru in the early COVID-19 pandemic, we analyzed 3472 viral genomes, of which 149 were from Peru. Phylogenomic analysis revealed multiple and independent introductions of the virus likely from Europe and Asia and a high diversity of genetic lineages circulating in Peru. In addition, we found evidence for community-driven transmission of SARS-CoV-2 as suggested by clusters of related viruses found in patients living in different regions of Peru.",

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AU - Valdivia, Faviola

AU - Rojas, Nancy

AU - Maturrano, Lenin

AU - Gavilán, Ronnie

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Phylogenomics reveals multiple introductions and early spread of SARS-CoV-2 into Peru

Abstract

Bibliographical note

Keywords

UN SDGs

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