Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venom

Francisco S. Schneider, Maria C. Starling, Clara G. Duarte, Ricardo Machado de Avila, Evanguedes Kalapothakis, Walter Silva Suarez, Benigno Tintaya, Karin Flores Garrido, Silvia Seraylan Ormachea, Armando Yarleque, César Bonilla, Carlos Chávez-Olórtegui

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Abstract

Bothrops andianus is a venomous snake found in the area of Machu Picchu (Peru). Its venom is not included in the antigenic pool used for production of the Peruvian anti-bothropic anti-venom. B. andianus venom can elicit many biological effects such as hemorrhage, hemolysis, proteolytic activity and lethality. The Peruvian anti-bothropic anti-venom displays consistent cross-reactivity with B. andianus venom, by ELISA and Western Blotting and is also effective in neutralizing the venom's toxic activities. © 2012 Elsevier Ltd.
Original languageAmerican English
Pages (from-to)1018-1021
Number of pages4
JournalToxicon
DOIs
StatePublished - 1 Nov 2012

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    Schneider, F. S., Starling, M. C., Duarte, C. G., Machado de Avila, R., Kalapothakis, E., Silva Suarez, W., Tintaya, B., Flores Garrido, K., Seraylan Ormachea, S., Yarleque, A., Bonilla, C., & Chávez-Olórtegui, C. (2012). Preclinical testing of Peruvian anti-bothropic anti-venom against Bothrops andianus snake venom. Toxicon, 1018-1021. https://doi.org/10.1016/j.toxicon.2012.06.018