TY - JOUR
T1 - Protection of pigs with cysticercosis from further infections after treatment with oxfendazole
AU - Gonzalez Zariquiey, Armando Emiliano
AU - Gavidia Chucan, Cesar Miguel
AU - Falcon, N.
AU - Bernal, T.
AU - Verastegui, M.
AU - Garcia, H. H.
AU - Gilman, R. H.
AU - Tsang, V. C.W.
AU - Mayta, H.
AU - Lopez Urbina, Maria Teresa
AU - Rodriguez, S.
AU - Martinez, M.
AU - Noh, J.
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2001
Y1 - 2001
N2 - Cysticercosis, the infection by the larvae of Taenia solium, is a major cause of acquired epilepsy in the world; it also causes significant economic loss because of contaminated pork. This disease is endemic in most developing countries and no control strategy has yet been proven efficient and sustainable. To further evaluate the full potential of single-dose oxfendazole treatment for pigs as a control measure, 20 pigs with cysticercosis were treated with oxfendazole and later matched with 41 naive pigs and exposed to a natural challenge in a hyperendemic area. New infections were found by serologic testing in 15 of the 32 controls (47%), and by the presence of cysts at necropsy in 12 of them (37%). Only minute residual scars were detected in the carcasses of oxfendazole-treated pigs. Pigs with cysticercosis, once treated with oxfendazole, are protected from new infections for at least three months.
AB - Cysticercosis, the infection by the larvae of Taenia solium, is a major cause of acquired epilepsy in the world; it also causes significant economic loss because of contaminated pork. This disease is endemic in most developing countries and no control strategy has yet been proven efficient and sustainable. To further evaluate the full potential of single-dose oxfendazole treatment for pigs as a control measure, 20 pigs with cysticercosis were treated with oxfendazole and later matched with 41 naive pigs and exposed to a natural challenge in a hyperendemic area. New infections were found by serologic testing in 15 of the 32 controls (47%), and by the presence of cysts at necropsy in 12 of them (37%). Only minute residual scars were detected in the carcasses of oxfendazole-treated pigs. Pigs with cysticercosis, once treated with oxfendazole, are protected from new infections for at least three months.
UR - http://www.scopus.com/inward/record.url?scp=0034897706&partnerID=8YFLogxK
U2 - 10.4269/ajtmh.2001.65.15
DO - 10.4269/ajtmh.2001.65.15
M3 - Artículo
C2 - 11504400
AN - SCOPUS:0034897706
VL - 65
SP - 15
EP - 18
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
SN - 0002-9637
IS - 1
ER -
