TY - JOUR
T1 - Respuesta inmunológica y bioquímica de ancianos con infección urinaria frente factores de virulencia en escherichia coli uropatógenas
AU - Gonzales-Rodriguez, Arturo Octavio
AU - Varillas, Stefany Fiorella Infante
AU - Pastor, Heli Jaime Barrón
AU - Mitma, Yesica Llimpe
AU - Canales, Doris Huerta
AU - Chero, Paolo Alberto Wong
AU - Gutierrez, César
AU - Cunza, Silvia Suarez
N1 - Publisher Copyright:
© 2020, Instituto Nacional de Salud. All rights reserved.
PY - 2020/7/1
Y1 - 2020/7/1
N2 - Descriptive study in which 24 urine samples from older adults with urinary tract infection (UTI), from nursing homes, were evaluated; in order to identify differences in the immune and biochemical response from older adults with UTI by Escherichia coli (E. coli) to major virulence factors in the pathogenesis of UTI. Iron concentration, TNF-α, IL-1β and antioxidant capacity in urine were determined. A relation was found between, an increase in iron and red blood cell concentration in urine, and the presence of the pap GII gene found in E. coli. It is concluded that older adults, with UTIs by E. coli with the gene pap GII, have increased tissue damage.
AB - Descriptive study in which 24 urine samples from older adults with urinary tract infection (UTI), from nursing homes, were evaluated; in order to identify differences in the immune and biochemical response from older adults with UTI by Escherichia coli (E. coli) to major virulence factors in the pathogenesis of UTI. Iron concentration, TNF-α, IL-1β and antioxidant capacity in urine were determined. A relation was found between, an increase in iron and red blood cell concentration in urine, and the presence of the pap GII gene found in E. coli. It is concluded that older adults, with UTIs by E. coli with the gene pap GII, have increased tissue damage.
KW - Antioxidants
KW - Cytokines (Source: MeSH NLM)
KW - Immunology
KW - Nursing Homes; Elderly; Uropathogenic Escherichia coli; Biomarkers; Virulence Factors
KW - Urinary tract infections
KW - Urine
UR - http://www.scopus.com/inward/record.url?scp=85096210511&partnerID=8YFLogxK
U2 - 10.17843/rpmesp.2020.373.4918
DO - 10.17843/rpmesp.2020.373.4918
M3 - Artículo
C2 - 33295557
AN - SCOPUS:85096210511
SN - 1726-4634
VL - 37
SP - 527
EP - 531
JO - Revista Peruana de Medicina de Experimental y Salud Publica
JF - Revista Peruana de Medicina de Experimental y Salud Publica
IS - 3
ER -