Immunological and biochemical response from older adults with urinary tract infection to uropathogenic escherichia coli virulence factors

Translated title of the contribution: Immunological and biochemical response from older adults with urinary tract infection to uropathogenic escherichia coli virulence factors

Arturo Octavio Gonzales-Rodriguez, Stefany Fiorella Infante Varillas, Heli Jaime Barron Pastor, Yesica Llimpe Mitma, Doris Huerta Canales, Paolo Alberto Wong Chero, César Gutierrez, Silvia Suarez Cunza

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Descriptive study in which 24 urine samples from older adults with urinary tract infection (UTI), from nursing homes, were evaluated; in order to identify differences in the immune and biochemical response from older adults with UTI by Escherichia coli (E. coli) to major virulence factors in the pathogenesis of UTI. Iron concentration, TNF-α, IL-1β and antioxidant capacity in urine were determined. A relation was found between, an increase in iron and red blood cell concentration in urine, and the presence of the pap GII gene found in E. coli. It is concluded that older adults, with UTIs by E. coli with the gene pap GII, have increased tissue damage.

Translated title of the contributionImmunological and biochemical response from older adults with urinary tract infection to uropathogenic escherichia coli virulence factors
Original languageEnglish
Pages (from-to)527-531
Number of pages5
JournalRevista Peruana de Medicina Experimental y Salud Publica
Volume37
Issue number3
DOIs
StatePublished - 1 Jul 2020

Bibliographical note

Publisher Copyright:
© 2020, Instituto Nacional de Salud. All rights reserved.

Keywords

  • Antioxidants
  • Cytokines (Source: MeSH NLM)
  • Immunology
  • Nursing Homes; Elderly; Uropathogenic Escherichia coli; Biomarkers; Virulence Factors
  • Urinary tract infections
  • Urine

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