SEOM clinical guideline on hereditary colorectal cancer (2019)

C. Guillén-Ponce, E. Lastra, I. Lorenzo-Lorenzo, T. Martín Gómez, R. Morales Chamorro, A. B. Sánchez-Heras, R. Serrano, M. C. Soriano Rodríguez, J. L. Soto, L. Robles

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

In the last 2 decades, clinical genetics on hereditary colorectal syndromes has shifted from just a molecular characterization of the different syndromes to the estimation of the individual risk of cancer and appropriate risk reduction strategies. In the last years, new specific therapies for some subgroups of patients have emerged as very effective alternatives. At the same time, germline multigene panel testing by next-generation sequencing (NGS) technology has become the new gold standard for molecular genetics.

Original languageEnglish
Pages (from-to)201-212
Number of pages12
JournalClinical and Translational Oncology
Volume22
Issue number2
DOIs
StatePublished - 1 Feb 2020

Bibliographical note

Publisher Copyright:
© 2020, The Author(s).

Keywords

  • Adenomatous polyposis
  • Colon cancer
  • Hereditary colorectal cancer
  • Lynch syndrome

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