Simultaneous Electrochemical Determination of Paracetamol and Allura Red in Pharmaceutical Doses and Food Using a Mo(VI) Oxide-Carbon Paste Microcomposite

Edgar Nagles; Mario Ceroni; Claudia Villanueva Huerta; John J. Hurtado

doi:10.1002/elan.202100261

Simultaneous Electrochemical Determination of Paracetamol and Allura Red in Pharmaceutical Doses and Food Using a Mo(VI) Oxide-Carbon Paste Microcomposite

Edgar Nagles, Mario Ceroni, Claudia Villanueva Huerta, John J. Hurtado

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

This work presents a new application for MoO₃ combined with carbon paste to prepare a microcomposite electrode (Mo(VI)_Ox/CPE) for the simultaneous determination of paracetamol (PCM) and Allure Red (AR) by square-wave voltammetry (SWV). The anodic peak currents for PCM and AR were 70.0 and 80.0 % high compared with an unmodified carbon paste electrode. The surface areas of Mo(VI)_Ox/CPE and CPE were evaluated by cyclic voltammetry. The detection limit were 0.14 and 0.38 μmol/L for PCM and AR respectively. The relative standard deviations (RSDs) were 2.0 % (n=7). Stability, shelf life and possible interferences were also evaluated with very acceptable results.

Original language	English
Pages (from-to)	2335-2344
Number of pages	10
Journal	Electroanalysis
Volume	33
Issue number	11
DOIs	https://doi.org/10.1002/elan.202100261
State	Published - Nov 2021
Externally published	Yes

Bibliographical note

Funding Information:
E. N and C. M. thank the Universidad Nacional Mayor de San Marcos (project C20071301and C21070961) for financial support. Additionally, J.H. thanks the Research Fund of the Faculty of Sciences of the Universidad de los Andes and the Chemistry Department for providing funding (project no. INV-2020-105-2038).

Funding Information:
E. N and C. M. thank the Universidad Nacional Mayor de San Marcos (project C20071301and C21070961) for financial support. Additionally, J.H. thanks the Research Fund of the Faculty of Sciences of the Universidad de los Andes and the Chemistry Department for providing funding (project no. INV‐2020‐105‐2038).

Publisher Copyright:
© 2021 Wiley-VCH GmbH

Keywords

allura red
carbon paste
molybdenum oxide
paracetamol
square wave voltammetry

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10.1002/elan.202100261

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title = "Simultaneous Electrochemical Determination of Paracetamol and Allura Red in Pharmaceutical Doses and Food Using a Mo(VI) Oxide-Carbon Paste Microcomposite",

abstract = "This work presents a new application for MoO3 combined with carbon paste to prepare a microcomposite electrode (Mo(VI)Ox/CPE) for the simultaneous determination of paracetamol (PCM) and Allure Red (AR) by square-wave voltammetry (SWV). The anodic peak currents for PCM and AR were 70.0 and 80.0 % high compared with an unmodified carbon paste electrode. The surface areas of Mo(VI)Ox/CPE and CPE were evaluated by cyclic voltammetry. The detection limit were 0.14 and 0.38 μmol/L for PCM and AR respectively. The relative standard deviations (RSDs) were 2.0 % (n=7). Stability, shelf life and possible interferences were also evaluated with very acceptable results.",

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AU - Nagles, Edgar

AU - Ceroni, Mario

AU - Villanueva Huerta, Claudia

AU - Hurtado, John J.

PY - 2021/11

Y1 - 2021/11

N2 - This work presents a new application for MoO3 combined with carbon paste to prepare a microcomposite electrode (Mo(VI)Ox/CPE) for the simultaneous determination of paracetamol (PCM) and Allure Red (AR) by square-wave voltammetry (SWV). The anodic peak currents for PCM and AR were 70.0 and 80.0 % high compared with an unmodified carbon paste electrode. The surface areas of Mo(VI)Ox/CPE and CPE were evaluated by cyclic voltammetry. The detection limit were 0.14 and 0.38 μmol/L for PCM and AR respectively. The relative standard deviations (RSDs) were 2.0 % (n=7). Stability, shelf life and possible interferences were also evaluated with very acceptable results.

AB - This work presents a new application for MoO3 combined with carbon paste to prepare a microcomposite electrode (Mo(VI)Ox/CPE) for the simultaneous determination of paracetamol (PCM) and Allure Red (AR) by square-wave voltammetry (SWV). The anodic peak currents for PCM and AR were 70.0 and 80.0 % high compared with an unmodified carbon paste electrode. The surface areas of Mo(VI)Ox/CPE and CPE were evaluated by cyclic voltammetry. The detection limit were 0.14 and 0.38 μmol/L for PCM and AR respectively. The relative standard deviations (RSDs) were 2.0 % (n=7). Stability, shelf life and possible interferences were also evaluated with very acceptable results.

KW - allura red

KW - carbon paste

KW - molybdenum oxide

KW - paracetamol

KW - square wave voltammetry

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Simultaneous Electrochemical Determination of Paracetamol and Allura Red in Pharmaceutical Doses and Food Using a Mo(VI) Oxide-Carbon Paste Microcomposite

Abstract

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Keywords

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