TY - JOUR
T1 - Transmisión intra-hogar en personas infectadas por SARS-CoV-2 (COVID-19) en Lima, Perú
AU - Angulo-Bazán, Yolanda
AU - Solis-Sánchez, Gilmer
AU - Cardenas, Fany
AU - Jorge, Ana
AU - Acosta, Joshi
AU - Cabezas, César
N1 - Publisher Copyright:
© 2021 Fundacao Oswaldo Cruz. All rights reserved.
PY - 2021
Y1 - 2021
N2 - The study aimed to describe the characteristics of SARS-CoV-2 transmission among members of households with a confirmed primary case of COVID-19 in districts with low burden of cases in Lima, Peru, compared to a district with high burden. This was a retrospective study with a secondary database review. Information was collected from an epidemiological surveillance activity in close contacts (household members) in 52 households in Lima, with a single member with COVID-19. Reevaluation was conducted in 10 households. The study evaluated epidemiological and clinical variables and their association with the result of the rapid serological test (presence of IgG, IgM, or both). Secondary cases were found in 40 households, representing mean identification of 49.9% per household. Secondary attack rate in household members was 53% (125 cases), and symptomatic individuals accounted for 77.6% of cases (symptomatic/asymptomatic ratio: 3.5). Presence of fever and/or chills was found in 40% of persons with positive test results, followed by sore throat with 39.2%. Ageusia and anosmia were present in 22.4% and 20.8% of cases, respectively. When there was a primary case of COVID-19 in the household, the secondary attack rate was 53%; however, in an important proportion of households there were no positive cases other than the primary case. The epidemiological and clinical findings were consistent with reports from other international series.
AB - The study aimed to describe the characteristics of SARS-CoV-2 transmission among members of households with a confirmed primary case of COVID-19 in districts with low burden of cases in Lima, Peru, compared to a district with high burden. This was a retrospective study with a secondary database review. Information was collected from an epidemiological surveillance activity in close contacts (household members) in 52 households in Lima, with a single member with COVID-19. Reevaluation was conducted in 10 households. The study evaluated epidemiological and clinical variables and their association with the result of the rapid serological test (presence of IgG, IgM, or both). Secondary cases were found in 40 households, representing mean identification of 49.9% per household. Secondary attack rate in household members was 53% (125 cases), and symptomatic individuals accounted for 77.6% of cases (symptomatic/asymptomatic ratio: 3.5). Presence of fever and/or chills was found in 40% of persons with positive test results, followed by sore throat with 39.2%. Ageusia and anosmia were present in 22.4% and 20.8% of cases, respectively. When there was a primary case of COVID-19 in the household, the secondary attack rate was 53%; however, in an important proportion of households there were no positive cases other than the primary case. The epidemiological and clinical findings were consistent with reports from other international series.
KW - COVID-19
KW - Contact Tracing
KW - Epidemiologic Surveillance Services
UR - http://www.scopus.com/inward/record.url?scp=85103143158&partnerID=8YFLogxK
U2 - 10.1590/0102-311X00238720
DO - 10.1590/0102-311X00238720
M3 - Artículo
C2 - 33729282
AN - SCOPUS:85103143158
SN - 0102-311X
VL - 37
JO - Cadernos de Saude Publica
JF - Cadernos de Saude Publica
IS - 3
M1 - e00238720
ER -