Tuberculosis que imita cáncer: Casos derivados al instituto nacional de enfermedades neoplásicas, Lima-Perú

Translated title of the contribution: Tuberculosis that mimics cancer: Cases referred to the national institute of neoplastic diseases, Lima-Peru

Juliana R. Villena-Suarez, William Vicente, Luis Taxa, Luis Cuéllar, Maria T. Nuñez-Butrón, Valeria Villegas, Miluska Castillo, Carlos A. Castañeda

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Tuberculosis (TB) is a major public health problem that, due to the clinical variability of its presentation, can be confused with cancer. The aim of this study was to identify the clinical-radiological characteristics and to describe the methodology that allowed to achieve a TB diagnosis in patients referred to the National Institute of Neoplastic Diseases (INEN) with a presumed diagnosis of cancer between 2014 and 2016. The study included 170 patients (52.4% men) with an average age of 41.1 years; 18% presented a history of contact with TB, and 5.9% had had the disease previously. The TB was pulmonary in 22.4% and extrapulmonary in 77.7% of patients. The most frequent symptoms were respiratory, tumor, weight loss, and neurological. The cancer diagnoses most frequently discarded were lymphoma, lung cancer, and brain cancer. The lesions that suggested a neoplasm indicated an advanced clinical stage in 63.5%. Therefore, it follows that the symptoms and images associated with TB can be confused with malignant neoplasms.

Translated title of the contributionTuberculosis that mimics cancer: Cases referred to the national institute of neoplastic diseases, Lima-Peru
Original languageSpanish
Pages (from-to)77-83
Number of pages7
JournalRevista Peruana de Medicina de Experimental y Salud Publica
Volume35
Issue number1
DOIs
StatePublished - 1 Jan 2018

Bibliographical note

Funding Information:
puede confundirse con una malignidad. El objetivo del estudio fue identificar las características clínico radiológicas y describir la metodología que permitió llegar al diagnóstico de TB en pacientes derivados con presunción diagnóstica de cáncer al Instituto Nacional de Enfermedades Neoplásicas (INEN) entre 2014 y 2016. Se incluyeron 170 pacientes (52,4 % hombres) con edad promedio de 41,1 años, 18 % presentaron antecedentes de contacto con TB y un 5,9 % tuvo previamente la enfermedad. La TB fue pulmonar en 22,4 % y extrapulmonar en 77,7 % de los pacientes. Los síntomas más frecuentes fueron respiratorios, tumoración, pérdida de peso y neurológicos. Los diagnósticos oncológicos descartados con mayor frecuencia fueron linfoma, cáncer pulmonar y cerebral. Las lesiones que sugerían una neoplasia indicaron un estadio clínico avanzado en el 63,5 %. Se concluye que los síntomas e imágenes asociados a TB pueden confundirse con neoplasias malignas.

Publisher Copyright:
© 2018, Instituto Nacional de Salud. All rights reserved.

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