Ultrasonic sorting in polymer-based microdevices: Application to early detection

I. Gonzalez, M. Tijero, J. Berganzo, A. Castillejo, Luis Soto Soto, A. Martin, M. Bouali

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

This work presents a study of polymeric microdevices implemented by piezoelectric actuators to carry out processes of sorting/separation on flowing suspensions, acting as acoustic tweezers to extract separately target particles or cells. They provide a low-cost and label-free platform, exploiting the difference of size, density and compressibility. Their ability to perform isolation of tumor cells from white blood cells makes them strategic tools for medical applications such as early detection or future tools for monitoring personalized chemotherapy. Polymer-based microdevices implemented by ultrasounds have been developed to isolate these cells with an efficiency level up to 70%. This technology is currently being optimized to reach efficiencies higher than 90% for its clinical application.

Original languageEnglish
Title of host publication2013 Pan American Health Care Exchanges, PAHCE 2013 - Conference, Workshops, and Exhibits. Cooperation / Linkages
Subtitle of host publicationAn Independent Forum for Patient Care and Technology Support
DOIs
StatePublished - 2013
Externally publishedYes
Event8th Pan American Health Care Exchanges Conference, PAHCE 2013 - Medellin, Colombia
Duration: 29 Apr 20134 May 2013

Publication series

NamePan American Health Care Exchanges, PAHCE
ISSN (Print)2327-8161
ISSN (Electronic)2327-817X

Conference

Conference8th Pan American Health Care Exchanges Conference, PAHCE 2013
CountryColombia
CityMedellin
Period29/04/134/05/13

Keywords

  • cell separation
  • metastasis
  • microfluidics
  • sensors and actuators
  • Sorting
  • ultrasonic Lab-on-chip

Fingerprint Dive into the research topics of 'Ultrasonic sorting in polymer-based microdevices: Application to early detection'. Together they form a unique fingerprint.

Cite this