Voltammetric determination of thiomersal with a new modified electrode based on a carbon paste electrode decorated with La2O3

Johisner Penagos-Llanos; Jorge A. Calderón; Edgar Nagles; Jhon J. Hurtado

doi:10.1016/j.jelechem.2018.12.040

Voltammetric determination of thiomersal with a new modified electrode based on a carbon paste electrode decorated with La₂O₃

Johisner Penagos-Llanos, Jorge A. Calderón, Edgar Nagles, Jhon J. Hurtado

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

A carbon-paste modified electrode decorated with La₂O₃ (LaO_x/CPE) is reported for the first time for the voltammetric determination of thiomersal (THM) content. The LaO_x/CPE surface was characterized using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and scanning electron microscopy (SEM). The presence of La₂O₃ on the surface of the carbon paste reduces the charge transfer resistance and improves the sensitivity toward the oxidation of THM, with an oxidation current increase of almost 60% and allows its determination by square-wave stripping voltammetry (SWSV). The detection limit (3σ/b) was 0.09 μmol L⁻¹ and the relative standard deviation was 2.5% (n = 7) with three different electrodes. Furthermore, the new sensor was applied in the detection of THM in vaccines and pharmaceutical dosages.

Original language	English
Pages (from-to)	536-542
Number of pages	7
Journal	Journal of Electroanalytical Chemistry
Volume	833
DOIs	https://doi.org/10.1016/j.jelechem.2018.12.040
State	Published - 15 Jan 2019
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2018 Elsevier B.V.

Keywords

Carbon paste
Lanthanum (III) oxide
Square wave stripping voltammetry
Thiomersal
Vaccines

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This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.jelechem.2018.12.040

Cite this

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title = "Voltammetric determination of thiomersal with a new modified electrode based on a carbon paste electrode decorated with La2O3 ",

abstract = "A carbon-paste modified electrode decorated with La2O3 (LaOx/CPE) is reported for the first time for the voltammetric determination of thiomersal (THM) content. The LaOx/CPE surface was characterized using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and scanning electron microscopy (SEM). The presence of La2O3 on the surface of the carbon paste reduces the charge transfer resistance and improves the sensitivity toward the oxidation of THM, with an oxidation current increase of almost 60% and allows its determination by square-wave stripping voltammetry (SWSV). The detection limit (3σ/b) was 0.09 μmol L−1 and the relative standard deviation was 2.5% (n = 7) with three different electrodes. Furthermore, the new sensor was applied in the detection of THM in vaccines and pharmaceutical dosages.",

keywords = "Carbon paste, Lanthanum (III) oxide, Square wave stripping voltammetry, Thiomersal, Vaccines",

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AU - Penagos-Llanos, Johisner

AU - Calderón, Jorge A.

AU - Nagles, Edgar

AU - Hurtado, Jhon J.

PY - 2019/1/15

Y1 - 2019/1/15

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AB - A carbon-paste modified electrode decorated with La2O3 (LaOx/CPE) is reported for the first time for the voltammetric determination of thiomersal (THM) content. The LaOx/CPE surface was characterized using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and scanning electron microscopy (SEM). The presence of La2O3 on the surface of the carbon paste reduces the charge transfer resistance and improves the sensitivity toward the oxidation of THM, with an oxidation current increase of almost 60% and allows its determination by square-wave stripping voltammetry (SWSV). The detection limit (3σ/b) was 0.09 μmol L−1 and the relative standard deviation was 2.5% (n = 7) with three different electrodes. Furthermore, the new sensor was applied in the detection of THM in vaccines and pharmaceutical dosages.

KW - Carbon paste

KW - Lanthanum (III) oxide

KW - Square wave stripping voltammetry

KW - Thiomersal

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