A novel fibrinolytic metalloproteinase, barnettlysin-I from Bothrops barnetti (barnett's pitviper) snake venom with anti-platelet properties

Keyphrases

• Metalloproteinases 100%
• Pitviper 100%
• Snake Venom 100%
• Bothrops 100%
• Hemostasis 100%
• Fibrinogen 100%
• Platelet Function 100%
• Antiplatelet 100%
• Fibrin Clot 100%
• Hemorrhagic Disease 50%
• Hydrolysis 50%
• Antithrombotic Effect 50%
• Venom 50%
• Collagen 50%
• Snake Venom Metalloproteinase 50%
• Laminin 50%
• Non-hemorrhagic 50%
• Molecular Inclusion 50%
• Plasma Fibronectin 50%
• Platelet Aggregation 50%
• GPIb 50%
• Biochemical Features 50%
• Ion Exchange Chromatography 50%
• Collagen-induced 50%
• Fibrin 50%
• Integrin 50%
• Polypeptide 50%
• Tissue Inhibitor of metalloproteinase-1 (TIMP-1) 50%
• IC50 50%
• Macroglobulin 50%
• Whole Blood 50%
• Platelet Activation 50%
• Proteinase 50%
• Active Components 50%
• Human Platelets 50%
• Collagen Binding 50%
• Collagen Type I 50%
• Ristocetin 50%
• Enzymatic Activity 50%
• Molecular Cations 50%
• Viperid Snakes 50%
• Drug Development 50%
• Fibrinolytic Agents 50%

Biochemistry, Genetics and Molecular Biology

• Metalloproteinase 100%
• Metalloendopeptidase 100%
• Bothrops 100%
• Platelet 100%
• Thrombocyte Function 66%
• Fibrinogen 66%
• Hemostasis 66%
• Fibrin Clot 66%
• Cation Exchange Chromatography 33%
• Enzymatic Hydrolysis 33%
• Fibronectin 33%
• Thrombocyte Aggregation 33%
• Thrombocyte Activation 33%
• Laminin 33%
• Protease 33%
• Viperidae 33%
• Ristocetin 33%
• Metalloprotease Inhibitor 33%
• Type I Collagen 33%
• Enzyme Activity 33%
• Integrin 33%
• IC50 33%
• Macroglobulin 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Fibrinolytic Agent 100%
• Bothrops 100%
• Snake Venom 100%
• Metalloproteinase 100%
• Antiplatelet 100%
• Anticoagulant Agent 50%
• Fibrinogen 50%
• Blood Stasis 50%
• Bleeding 25%
• Proteinase 25%
• Collagen Type 1 25%
• Ethylenediaminetetraacetic Acid 25%
• Ristocetin 25%
• Drug Development 25%
• Laminin 25%
• Fibronectin 25%
• Viperidae 25%
• Alpha 2 Macroglobulin 25%
• IC50 25%
• Polypeptide 25%
• Integrin 25%
• Metalloproteinase Inhibitor 25%