Discrepancies between cerebral computed tomography and western blot in the diagnosis of neurocysticercosis

H. H. Garcia; G. Herrera; R. H. Gilman; V. C.W. Tsang; J. B. Pilcher; J. F. Diaz; E. J. Candy; E. Miranda; J. Naranjo; P. Torres; C. Gallo; C. Careamo; M. Verastegui; T. Montenegro; M. Alvarez; C. Evans; A. E. Gonzales; M. Castro; A. Guerron

doi:10.4269/ajtmh.1994.50.152

Discrepancies between cerebral computed tomography and western blot in the diagnosis of neurocysticercosis

H. H. Garcia, G. Herrera, R. H. Gilman, V. C.W. Tsang, J. B. Pilcher, J. F. Diaz, E. J. Candy, E. Miranda, J. Naranjo, P. Torres, C. Gallo, C. Careamo, M. Verastegui, T. Montenegro, M. Alvarez, C. Evans, A. E. Gonzales, M. Castro, A. Guerron

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64 Citas (Scopus)

Resumen

Serum samples from sequential patients who underwent cerebral computed axial tomography (CT) scan in a Peruvian radiologic clinic were tested by the highly sensitive and specific enzyme-linked immunoelectrotransfer blot (EITB) test to detect antibodies to Taenia solium. The results of the EITB test were compared with those obtained by CT scan for the diagnosis of neurocysticercosis. Of the 383 patients sampled, 32 (8%) were seropositive. The results of CT and EITB were frequently discrepant. When compared with the EITB assay, the CT scan was 44% sensitive and 95% specific. The sensitivity of CT increased to 63% if less specific images (single calcifications, granulomas, or hydrocephalus) were included. The CT scan for diagnosis of cysticercosis can best be used in conjunction with a reliable serologic test such as the EITB.

Idioma original	Inglés
Páginas (desde-hasta)	152-157
Número de páginas	6
Publicación	American Journal of Tropical Medicine and Hygiene
Volumen	50
N.º	2
DOI	https://doi.org/10.4269/ajtmh.1994.50.152
Estado	Publicada - 1994
Publicado de forma externa	Sí

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Garcia, H. H., Herrera, G., Gilman, R. H., Tsang, V. C. W., Pilcher, J. B., Diaz, J. F., Candy, E. J., Miranda, E., Naranjo, J., Torres, P., Gallo, C., Careamo, C., Verastegui, M., Montenegro, T., Alvarez, M., Evans, C., Gonzales, A. E., Castro, M., & Guerron, A. (1994). Discrepancies between cerebral computed tomography and western blot in the diagnosis of neurocysticercosis. American Journal of Tropical Medicine and Hygiene, 50(2), 152-157. https://doi.org/10.4269/ajtmh.1994.50.152

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title = "Discrepancies between cerebral computed tomography and western blot in the diagnosis of neurocysticercosis",

abstract = "Serum samples from sequential patients who underwent cerebral computed axial tomography (CT) scan in a Peruvian radiologic clinic were tested by the highly sensitive and specific enzyme-linked immunoelectrotransfer blot (EITB) test to detect antibodies to Taenia solium. The results of the EITB test were compared with those obtained by CT scan for the diagnosis of neurocysticercosis. Of the 383 patients sampled, 32 (8%) were seropositive. The results of CT and EITB were frequently discrepant. When compared with the EITB assay, the CT scan was 44% sensitive and 95% specific. The sensitivity of CT increased to 63% if less specific images (single calcifications, granulomas, or hydrocephalus) were included. The CT scan for diagnosis of cysticercosis can best be used in conjunction with a reliable serologic test such as the EITB.",

author = "Garcia, {H. H.} and G. Herrera and Gilman, {R. H.} and Tsang, {V. C.W.} and Pilcher, {J. B.} and Diaz, {J. F.} and Candy, {E. J.} and E. Miranda and J. Naranjo and P. Torres and C. Gallo and C. Careamo and M. Verastegui and T. Montenegro and M. Alvarez and C. Evans and Gonzales, {A. E.} and M. Castro and A. Guerron",

year = "1994",

doi = "10.4269/ajtmh.1994.50.152",

language = "Ingl{\'e}s",

volume = "50",

pages = "152--157",

journal = "American Journal of Tropical Medicine and Hygiene",

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Garcia, HH, Herrera, G, Gilman, RH, Tsang, VCW, Pilcher, JB, Diaz, JF, Candy, EJ, Miranda, E, Naranjo, J, Torres, P, Gallo, C, Careamo, C, Verastegui, M, Montenegro, T, Alvarez, M, Evans, C, Gonzales, AE, Castro, M & Guerron, A 1994, 'Discrepancies between cerebral computed tomography and western blot in the diagnosis of neurocysticercosis', American Journal of Tropical Medicine and Hygiene, vol. 50, n.º 2, pp. 152-157. https://doi.org/10.4269/ajtmh.1994.50.152

TY - JOUR

T1 - Discrepancies between cerebral computed tomography and western blot in the diagnosis of neurocysticercosis

AU - Garcia, H. H.

AU - Herrera, G.

AU - Gilman, R. H.

AU - Tsang, V. C.W.

AU - Pilcher, J. B.

AU - Diaz, J. F.

AU - Candy, E. J.

AU - Miranda, E.

AU - Naranjo, J.

AU - Torres, P.

AU - Gallo, C.

AU - Careamo, C.

AU - Verastegui, M.

AU - Montenegro, T.

AU - Alvarez, M.

AU - Evans, C.

AU - Gonzales, A. E.

AU - Castro, M.

AU - Guerron, A.

PY - 1994

Y1 - 1994

N2 - Serum samples from sequential patients who underwent cerebral computed axial tomography (CT) scan in a Peruvian radiologic clinic were tested by the highly sensitive and specific enzyme-linked immunoelectrotransfer blot (EITB) test to detect antibodies to Taenia solium. The results of the EITB test were compared with those obtained by CT scan for the diagnosis of neurocysticercosis. Of the 383 patients sampled, 32 (8%) were seropositive. The results of CT and EITB were frequently discrepant. When compared with the EITB assay, the CT scan was 44% sensitive and 95% specific. The sensitivity of CT increased to 63% if less specific images (single calcifications, granulomas, or hydrocephalus) were included. The CT scan for diagnosis of cysticercosis can best be used in conjunction with a reliable serologic test such as the EITB.

AB - Serum samples from sequential patients who underwent cerebral computed axial tomography (CT) scan in a Peruvian radiologic clinic were tested by the highly sensitive and specific enzyme-linked immunoelectrotransfer blot (EITB) test to detect antibodies to Taenia solium. The results of the EITB test were compared with those obtained by CT scan for the diagnosis of neurocysticercosis. Of the 383 patients sampled, 32 (8%) were seropositive. The results of CT and EITB were frequently discrepant. When compared with the EITB assay, the CT scan was 44% sensitive and 95% specific. The sensitivity of CT increased to 63% if less specific images (single calcifications, granulomas, or hydrocephalus) were included. The CT scan for diagnosis of cysticercosis can best be used in conjunction with a reliable serologic test such as the EITB.

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DO - 10.4269/ajtmh.1994.50.152

M3 - Artículo

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AN - SCOPUS:0028333745

SN - 0002-9637

VL - 50

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EP - 157

JO - American Journal of Tropical Medicine and Hygiene

JF - American Journal of Tropical Medicine and Hygiene

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ER -

Discrepancies between cerebral computed tomography and western blot in the diagnosis of neurocysticercosis

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