Efecto de la masticación sobre la memoria y aprendizaje espacial en ratones adultos y seniles

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

1 Cita (Scopus)

Resumen

Introduction: Chewing is a peripheral activity that positively influences the central nervous system (CNS). However, despite the different studies carried out, it is still not clear how chewing affects cognitive processes. Because of this, was trying to find the effect of chewing on memory and spatial learning in adult and senile mice. Methods: A group of 16 adult and senile mice were randomized into 2 subgroups of 8 mice each group. One subgroup was fed with conventional grainy diet for mice (normal chewing subgroup), the other subgroup was fed dietary powder (deficient chewing subgroup). During 2 months each subgroup was submitted to their respective diet. Adult mice at 7 months of age and senile at 12 months of age were evaluated in the Morris' water maze; through of the acquisition phase and the probe test of memory and spatial learning. Results: Adult mice with normal chewing showed better memory acquisition and spatial learning with respect to mice with deficient chewing on the first day of evaluation (p = 0.035). When grouping the mice in the same type of chewing, in the subgroups under normal chewing, a better acquisition of memory and spatial learning was found in the adult subgroup on than in the senile subgroup (p < 0.05). Conclusions: Normal chewing had a positive effect on the acquisition of spatial information in adult mice.

Título traducido de la contribuciónEffect of chewing on memory and spatial learning in adult and senile mice
Idioma originalEspañol
Páginas (desde-hasta)149-157
Número de páginas9
PublicaciónRevista Chilena de Neuro-Psiquiatria
Volumen57
N.º2
DOI
EstadoPublicada - 2019
Publicado de forma externa

Nota bibliográfica

Publisher Copyright:
© 2019 Sociedad de Neurologia Psiquiatria y Neurocirugia. All rights reserved.

Palabras clave

  • Chewing
  • Diet
  • Male albino mice
  • Memory and spatial learning
  • Morris' water maze

Huella

Profundice en los temas de investigación de 'Efecto de la masticación sobre la memoria y aprendizaje espacial en ratones adultos y seniles'. En conjunto forman una huella única.

Citar esto