The effect of ketoprofen, an antiprostaglandin substance that inhibits the enzyme ciclooxigenase, on the mean pulmonary arterial pressure (mPAP) was evaluated in 10, male Jersey calves, of 1-2 months of age. Calves were born at sea level and exposed during 3 days to an environmental hypoxia of 3,320 m of high altitude. A group of 5 animals received destiled water as placebo (Control group), and other group received ketoprofen in dose of 3 mg/kg body weight for 5 consecutive days while at sea level (Treated group). The mPAP was measured by cardiac cateterism at sea level and 3 days after arriving to the high altitude. The mean values of mPAP (mm Hg) at sea level were: Control group 19.00 ± 0.94 and Treated group 21.00 ± 3.39; whereas at the high altitude were: Control group 39.50 ± 6.00 and Treated group 31.25 ± 5.70, and without significant differences. When data of the two groups were joined and analysed together, the values for mPAP at sea level (20.00 ± 2.68) were statistically different (p<0.05) from those at day 3 of exposition to high altitude (35.28 ± 7.16). The results suggested that ketoprofen had not effect on mPAP in Jersey calves exposed during 3 days at high altitude hypoxia.

Título traducido de la contribuciónEffect of ketoprofen on the pulmonary arterial pressurein Jersey calves subjected to high altitud hypoxia
Idioma originalEspañol
Páginas (desde-hasta)94-98
Número de páginas5
PublicaciónRevista de Investigaciones Veterinarias del Peru
EstadoPublicada - 2007

Nota bibliográfica

Publisher Copyright:
© 2007 Universidad Nacional Mayor de San Marcos. All rights reserved.

Palabras clave

  • Cardiac cateterism
  • Hypoxia
  • Jersey calves
  • Ketoprofen
  • Mean pulmonary arterial pressure


Profundice en los temas de investigación de 'Efecto del ketoprofeno sobre la presión arterial pulmonar en terneros jersey sometidos a hipoxia de la altura'. En conjunto forman una huella única.

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