Enterectomía yeyunal revestida con xenoinjerto de pericardio bovino en un modelo canino

Ceesar Nilthom Aguilar Guevara, Gianfranco Espil Incil, Natalia Soledad Gonzalez Gavidia, Octavio Merino Minchán, Cristina Tatiana García Barjoveanu, Diego Pier Allcahuamán Matienzo, Alfredo Delgado Castro

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

1 Cita (Scopus)


The aim of this study was to evaluate the alteration of the cellular components of the peritoneal lavage and to characterize the cicatricial remodelling, at the macro and microscopic level, produced by the experimental use of bovine pericardium xenograft (XPB) not treated as a lining of the end to end-jejunal terminal anastomosis in a canine model. Nine canines between 4 and 6 years of age, 15-30 kg of weight, and both sexes were randomly distributed in three experimental groups (A, B and C) of three animals each, to which an untreated XPB was placed as a lining of the jejunal enterectomy. Each group underwent a second celiotomy at 5, 10 and 30 days post-surgery, respectively. The results of the analysis of the cellular components of the peritoneal fluid showed a significant increase in lymphocytes, macrophages and eosinophils 30 days after the surgery and to a lesser extent 10 and 5 days after the intervention. In the macroscopic pathology, none of the groups denoted the presence of leakage, stenosis, abscesses or signs of peritonitis, nor was visualization of contraction or displacement of the XPB, but adhesion of the omentum was evident. The histopathology revealed a reaction to a foreign body of minimal to moderate, but totally compatible with life and almost surpassed 30 days after the surgery. It is concluded that the technique of jejunal anastomosis in canines coated with untreated XPB is viable and effective because it does not generate severe cellular infiltration against possible harmful cellular antigens or calcification processes. In addition, it does not alter the functions of intestinal digestion, secretion and absorption.

Título traducido de la contribuciónJejunal enterectomy covered with bovine pericardium xenograft in a canine model
Idioma originalEspañol
Páginas (desde-hasta)795-809
Número de páginas15
PublicaciónRevista de Investigaciones Veterinarias del Peru
EstadoPublicada - 2019

Nota bibliográfica

Publisher Copyright:
© 2019 Universidad Nacional Mayor de San Marcos. All rights reserved.

Palabras clave

  • Bovine pericardium
  • Enterectomy
  • Jejunal anastomosis
  • Xenograft


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