TY - JOUR
T1 - Experimental porcine cysticercosis using infected beetles with Taenia solium eggs
AU - for the Cysticercosis Working Group in Peru
AU - Gomez-Puerta, Luis A.
AU - Garcia, Hector H.
AU - Gonzalez, Armando E.
N1 - Publisher Copyright:
© 2018 Elsevier B.V.
PY - 2018/7
Y1 - 2018/7
N2 - Beetles are intermediate hosts for human and animal parasites, and several beetle species have been shown to carry Taenia eggs. An experimental porcine cysticercosis infection model was developed using beetles (Ammophorus rubripes) infected with Taenia solium eggs and then using these beetles for oral pig challenge. A total of 18 three months-old Landrace pigs were divided in four groups. Pigs from groups 1, 2, and 3 (n = 6 pigs per group) were challenged with one, three, and six beetles infected with T. solium eggs, containing approximately 52, 156 or 312 eggs respectively. Pigs were necropsied 12 weeks after infection to assess the presence of T. solium metacestode. Porcine cysticercosis by T. solium was produced in 17 out of 18 pigs (94.4%) challenged with infected beetles, all infected pigs had viable cysts. Only one pig from group 1 was negative to the presence of cysts. The median number of metacestodes per pig in groups 1, 2, and 3 were 2 (range 0–71), 26 (range 5–33) and 40 cysts (range 4–111), respectively. Experimental porcine cysticercosis infection is consistently obtained using beetles as mechanical vectors for T. solium eggs.
AB - Beetles are intermediate hosts for human and animal parasites, and several beetle species have been shown to carry Taenia eggs. An experimental porcine cysticercosis infection model was developed using beetles (Ammophorus rubripes) infected with Taenia solium eggs and then using these beetles for oral pig challenge. A total of 18 three months-old Landrace pigs were divided in four groups. Pigs from groups 1, 2, and 3 (n = 6 pigs per group) were challenged with one, three, and six beetles infected with T. solium eggs, containing approximately 52, 156 or 312 eggs respectively. Pigs were necropsied 12 weeks after infection to assess the presence of T. solium metacestode. Porcine cysticercosis by T. solium was produced in 17 out of 18 pigs (94.4%) challenged with infected beetles, all infected pigs had viable cysts. Only one pig from group 1 was negative to the presence of cysts. The median number of metacestodes per pig in groups 1, 2, and 3 were 2 (range 0–71), 26 (range 5–33) and 40 cysts (range 4–111), respectively. Experimental porcine cysticercosis infection is consistently obtained using beetles as mechanical vectors for T. solium eggs.
KW - Ammophorus rubripes
KW - Beetle
KW - Porcine cysticercosis
KW - Taenia solium
UR - http://www.scopus.com/inward/record.url?scp=85045182003&partnerID=8YFLogxK
U2 - 10.1016/j.actatropica.2018.04.003
DO - 10.1016/j.actatropica.2018.04.003
M3 - Artículo
C2 - 29626435
AN - SCOPUS:85045182003
SN - 0001-706X
VL - 183
SP - 92
EP - 94
JO - Acta Tropica
JF - Acta Tropica
ER -