Enterobacterias productoras de betalactamasas de espectro extendido en muestras fecales en el instituto nacional de salud del niño, Perú

Fabiola Colquechagua Aliaga, Carlos Sevilla Andrade, Edgar Gonzales Escalante

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

8 Citas (Scopus)

Resumen

Objectives. To describe the frequency of extended-spectrum beta-lactamase (ESBL)-producing enterobacteriaceae in fecal samples at the National Institute of Child Health, Lima, Peru. Materials and methods. Stool samples received between July 2012 and March 2013 with colonies suspected to be ESBL-producing enterobacteriaceae that developed in Karmali agar were analyzed. Conventional methods were performed for biochemical identification and the confirmation of the ESBL phenotype. Genotypic analysis to detect the beta-lactamase gene CTX-M family was performed by PCR. Results. Of the 235 fecal samples analyzed, 64.2% of ESBL-producing enterobacteria was isolated being 86.1% Escherichia coli, 7.9% Klebsiella pneumoniae, 2.6% Salmonella sp, 2.0% Enterobacter cloacae, and 1.3% Proteus mirabilis. 89.1% of the ESBL-producing enterobacteria presented the CTX-M gene. We found high resistance to nalidixic acid 84.8%, 74.2% ciprofloxacin and trimethoprim-sulfamethoxazole 81.5%.The resistance to amikacin was 1.3% and all isolates were susceptible to imipenem and meropenem. Conclusions. A high frequency of ESBL-producing enterobacteria was found in fecal samples of outpatients seen in the outpatient and emergency departments of the National Institute of Child Health of Peru.

Título traducido de la contribuciónExtended-spectrum beta-lactamase (Esbl)-producing enterobacteriaceae in fecal samples at the national institute of child health, Peru
Idioma originalEspañol
Páginas (desde-hasta)26-32
Número de páginas7
PublicaciónRevista Peruana de Medicina de Experimental y Salud Publica
Volumen32
N.º1
DOI
EstadoPublicada - 2015

Nota bibliográfica

Publisher Copyright:
© 2015, Instituto Nacional de Salud. All rights reserved.

Palabras clave

  • Beta-Lactamasa I
  • Enterobacteria
  • Feces

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