Cinética e avidez de anticorpos (IgG) anti-Toxocara em coelhos experimentalmente infectados com Toxocara canis

Lundia Luara Cavalcante Bin, Vamilton Alvares Santarém, Cecília Braga Laposy, Guita Rubinsky-Elefant, William Henry Roldán, Rogério Giuffrida

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

3 Citas (Scopus)

Resumen

An evaluation was made of the kinetics and avidity of anti-Toxocara antibodies (IgG) in rabbits experimentally infected with embryonated Toxocara canis eggs. Seventeen four month old New Zealand White rabbits were distributed into two groups. In the experimental group, twelve rabbits were infected orally with 1,000 embryonated T. canis eggs. A second group (n = 5), uninfected, was used as a control. Serum samples were collected for analysis on days 7, 14, 21, 28 and 60 post-infection (DPI). An indirect ELISA test was performed to evaluate the reactivity index (RI) of IgG anti-T. canis antibodies and to calculate the avidity index (AI). The animals showed seroconversion from the 14th DPI, with high AI (over 50%) except for one animal, which presented an intermediate AI. At 60 DPI, all the animals were seropositive and maintained a high AI. The data indicated that specific IgG antibodies formed early (14 DPI) in rabbits infected with T. canis, with a high avidity index that persisted throughout the course of the infection.

Título traducido de la contribuciónKinetics and avidity of anti-toxocara antibodies (IgG) in rabbits experimentally infected with toxocara canis
Idioma originalPortugués
Páginas (desde-hasta)99-104
Número de páginas6
PublicaciónRevista Brasileira de Parasitologia Veterinaria
Volumen25
N.º1
DOI
EstadoPublicada - 1 ene. 2016

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© 2016, Brazilain Coll Veterinary Parasitology. All rights reserved.

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