TY - JOUR
T1 - Malignant lymphoma of the oral cavity and the maxillofacial region
T2 - Overall survival prognostic factors
AU - Guevara-Canales, Janet Ofelia
AU - Morales-Vadillo, Rafael
AU - Sacsaquispe-Contreras, Sonia Julia
AU - Barrionuevo-Cornejo, Carlos
AU - Montes-Gil, Jaime
AU - Cava-Vergiú, Carlos Enrique
AU - Soares, Fernando Augusto
AU - Chaves-Netto, Henrique Duque de Miranda
AU - Chaves, Maria das Graças Afonso Miranda
PY - 2013/7/1
Y1 - 2013/7/1
N2 - Objective: To identify the overall survival and prognostic factors of malignant lymphoma of the oral cavity and the maxillofacial region. Study Design: Clinical records data were obtained in order to determine overall survival at 2 and 5 years, the individual survival percentage of each possible prognostic factor with the actuarial technique, and the survival regarding the possible prognostic factors with the actuarial technique and the Log-rank and Cox's regression tests. Results: Of 151 subjects, an overall survival was 60% at 2 years, and 45% at 5 years. The multivariate analysis demonstrated statistically significant differences for clinical stage (p=0.002), extranodal involvement (p=0.030), presence of human immunodeficiency virus (p=0.032), and presence of Epstein-Barr virus (p=0.010). Conclusion: The advanced clinical stage and the larger number of involved extranodular sites are related to a lower overall survival, as well as, the presence of previous infections such as the human immunodeficiency and the Epstein-Barr virus.
AB - Objective: To identify the overall survival and prognostic factors of malignant lymphoma of the oral cavity and the maxillofacial region. Study Design: Clinical records data were obtained in order to determine overall survival at 2 and 5 years, the individual survival percentage of each possible prognostic factor with the actuarial technique, and the survival regarding the possible prognostic factors with the actuarial technique and the Log-rank and Cox's regression tests. Results: Of 151 subjects, an overall survival was 60% at 2 years, and 45% at 5 years. The multivariate analysis demonstrated statistically significant differences for clinical stage (p=0.002), extranodal involvement (p=0.030), presence of human immunodeficiency virus (p=0.032), and presence of Epstein-Barr virus (p=0.010). Conclusion: The advanced clinical stage and the larger number of involved extranodular sites are related to a lower overall survival, as well as, the presence of previous infections such as the human immunodeficiency and the Epstein-Barr virus.
KW - Lymphoma
KW - Oral cavity
KW - Survival
UR - http://www.scopus.com/inward/record.url?scp=84880417998&partnerID=8YFLogxK
U2 - 10.4317/medoral.18903
DO - 10.4317/medoral.18903
M3 - Artículo
C2 - 23722134
AN - SCOPUS:84880417998
SN - 1698-4447
VL - 18
SP - e619-e626
JO - Medicina Oral, Patologia Oral y Cirugia Bucal
JF - Medicina Oral, Patologia Oral y Cirugia Bucal
IS - 4
ER -