Compromiso parametrial en pacientes con cÁncer de cÉrvix ib-1 tratadas con histerectomÍa radical en PerÚ

Carlos Urrutia, Carlos Santos, Albert Zevallos, Aldo López, Absalón Montoya, Marco Sánchez, Henry Valdivia, Carlos Velarde, Raúl Mantilla, Esperanza Milla, Carlos Arturo Castañeda Altamirano, Mayer Zaharia, Manuel Álvarez

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

Resumen

Objectives. To assess the frequency and factors associated with parametrial involvement (PI) in patients with cervical cancer IB1 who underwent radical hysterectomy (RH) at the National Institute of Neoplastic Diseases in Peru. Materials and methods. Cross-sectional study of 214 patients with cervical cancer IB1 undergoing RH with pelvic lymphadenectomy between 2007 and 2012. The population was compared with and without clinicopathological variables associated with PI such as age, tumor size, depth of infiltration, histological grade and pelvic lymph node involvement. Results. Ten patients (4.6%) had PI. Multivariate analysis showed that the depth of invasion (OR 8.37, 95% CI 1.24-56.41, p=0.029) and pelvic node involvement (OR 18.03; 95% CI 3.30-98.44, p=0.001) were all independent predictors of PI. The presence of tumor size ≤ 2 cm, invasion ≤ 10 mm, absence of lymphovascular permeation and absence of nodal involvement identified 97 patients at low risk of PI, none of whom had PI pathology. Conclusions. We confirmed the low frequency of PI in the cervical cancer IB1 subgroup and its association with the depth of invasion and lymph node involvement suggested in previous studies. This information will allow the identification of a subgroup of patients at low risk of PI for less radical surgery in our institution.

Título traducido de la contribuciónParametrial involvement in cervical cancer ib1 patients treated with radical hysterectomy in Peru
Idioma originalEspañol
Páginas (desde-hasta)431-436
Número de páginas6
PublicaciónRevista Peruana de Medicina de Experimental y Salud Publica
Volumen31
N.º3
EstadoPublicada - 2014
Publicado de forma externa

Palabras clave

  • Hysterectomy
  • Lymph node excision
  • Uterine cervical neoplasms

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