Phenotypic detection of antimicrobial resistance mechanisms of Escherichia coli isolates from enteric infections in pigs from technified farms

C. Michelle Monterroso, R. Guillermo Salvatierra, S. André Sedano, E. Sonia Calle

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

Resumen

© 2019 Universidad Nacional Mayor de San Marcos. All rights reserved. The aim of this study was to detect the antimicrobial resistance mechanisms of 36 Escherichia coli isolates to beta-lactams, quinolones and aminoglycosides using the Kirby-Bauer technique. Thirty-six E. coli isolates from pigs of technified production farms obtained during the 2010-2015 period were used. Fifteen antimicrobials of importance in human and veterinary medicine were tested. The isolates showed resistance mainly to nalidixic acid (89%, 32/36), cloxacillin (83%, 30/36) and amoxicillin-clavulanic acid (69%, 25/36). Only 3% (1/36) were AmpC producers, 42% (15/36) showed a possible mutation in gyrA and 14% (5/36) at least two possible mutations in gyrA or gyrA+parC. In addition, 33% (12/36) showed high probabilities of presence of qnr genes. The enzymes associated to aminoglycoside resistance mechanism were positive in 39% (14/36) to AAC (6’), 28% (10/36) to ANT (2") and 11% (4/36) to AAC (3) IV.
Idioma originalInglés estadounidense
Páginas (desde-hasta)455-464
Número de páginas10
PublicaciónRevista de Investigaciones Veterinarias del Peru
DOI
EstadoPublicada - 1 ene 2019

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