Phylogenomics reveals multiple introductions and early spread of SARS-CoV-2 into Peru

Eduardo Juscamayta-López; Dennis Carhuaricra; David Tarazona; Faviola Valdivia; Nancy Rojas; Lenin Maturrano; Ronnie Gavilán

doi:10.1002/jmv.27167

Phylogenomics reveals multiple introductions and early spread of SARS-CoV-2 into Peru

Eduardo Juscamayta-López, Dennis Carhuaricra, David Tarazona, Faviola Valdivia, Nancy Rojas, Lenin Maturrano, Ronnie Gavilán

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Resumen

Peru has become one of the countries with the highest mortality rates from the current coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To investigate early transmission events and the genomic diversity of SARS-CoV-2 isolates circulating in Peru in the early COVID-19 pandemic, we analyzed 3472 viral genomes, of which 149 were from Peru. Phylogenomic analysis revealed multiple and independent introductions of the virus likely from Europe and Asia and a high diversity of genetic lineages circulating in Peru. In addition, we found evidence for community-driven transmission of SARS-CoV-2 as suggested by clusters of related viruses found in patients living in different regions of Peru.

Idioma original	Inglés
Páginas (desde-hasta)	5961-5968
Número de páginas	8
Publicación	Journal of Medical Virology
Volumen	93
N.º	10
DOI	https://doi.org/10.1002/jmv.27167
Estado	Publicada - oct. 2021
Publicado de forma externa	Sí

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abstract = "Peru has become one of the countries with the highest mortality rates from the current coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To investigate early transmission events and the genomic diversity of SARS-CoV-2 isolates circulating in Peru in the early COVID-19 pandemic, we analyzed 3472 viral genomes, of which 149 were from Peru. Phylogenomic analysis revealed multiple and independent introductions of the virus likely from Europe and Asia and a high diversity of genetic lineages circulating in Peru. In addition, we found evidence for community-driven transmission of SARS-CoV-2 as suggested by clusters of related viruses found in patients living in different regions of Peru.",

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AU - Carhuaricra, Dennis

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AU - Valdivia, Faviola

AU - Rojas, Nancy

AU - Maturrano, Lenin

AU - Gavilán, Ronnie

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Phylogenomics reveals multiple introductions and early spread of SARS-CoV-2 into Peru

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